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p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa
TPPP (tubulin polymerization promoting protein)-like proteins contain one or more p25alpha (Pfam05517) domains. TPPP-like proteins occur in different types as determined by their length (e.g., long-, short-, truncated-, and fungal-type TPPP) and include the protein apicortin, which possesses another...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304595/ https://www.ncbi.nlm.nih.gov/pubmed/37375031 http://dx.doi.org/10.3390/microorganisms11061528 |
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author | Orosz, Ferenc |
author_facet | Orosz, Ferenc |
author_sort | Orosz, Ferenc |
collection | PubMed |
description | TPPP (tubulin polymerization promoting protein)-like proteins contain one or more p25alpha (Pfam05517) domains. TPPP-like proteins occur in different types as determined by their length (e.g., long-, short-, truncated-, and fungal-type TPPP) and include the protein apicortin, which possesses another domain, doublecortin (DCX, Pfam 03607). These various TPPP-like proteins are found in various phylogenomic groups. In particular, short-type TPPPs and apicortin are well-represented in the Myzozoa, which include apicomplexans and related taxa, chrompodellids, dinoflagellates, and perkinsids. The long-, truncated-, and fungal-type TPPPs are not found in the myzozoans. Apicortins are found in all apicomplexans except one piroplasmid species, present in several other myzozoans, and seem to be correlated with the conoid and apical complex. Short-type TPPPs are predominantly found in myzozoans that have flagella, suggesting a role in flagellum assembly or structure. |
format | Online Article Text |
id | pubmed-10304595 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103045952023-06-29 p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa Orosz, Ferenc Microorganisms Review TPPP (tubulin polymerization promoting protein)-like proteins contain one or more p25alpha (Pfam05517) domains. TPPP-like proteins occur in different types as determined by their length (e.g., long-, short-, truncated-, and fungal-type TPPP) and include the protein apicortin, which possesses another domain, doublecortin (DCX, Pfam 03607). These various TPPP-like proteins are found in various phylogenomic groups. In particular, short-type TPPPs and apicortin are well-represented in the Myzozoa, which include apicomplexans and related taxa, chrompodellids, dinoflagellates, and perkinsids. The long-, truncated-, and fungal-type TPPPs are not found in the myzozoans. Apicortins are found in all apicomplexans except one piroplasmid species, present in several other myzozoans, and seem to be correlated with the conoid and apical complex. Short-type TPPPs are predominantly found in myzozoans that have flagella, suggesting a role in flagellum assembly or structure. MDPI 2023-06-08 /pmc/articles/PMC10304595/ /pubmed/37375031 http://dx.doi.org/10.3390/microorganisms11061528 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Orosz, Ferenc p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa |
title | p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa |
title_full | p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa |
title_fullStr | p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa |
title_full_unstemmed | p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa |
title_short | p25alpha Domain-Containing Proteins of Apicomplexans and Related Taxa |
title_sort | p25alpha domain-containing proteins of apicomplexans and related taxa |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304595/ https://www.ncbi.nlm.nih.gov/pubmed/37375031 http://dx.doi.org/10.3390/microorganisms11061528 |
work_keys_str_mv | AT oroszferenc p25alphadomaincontainingproteinsofapicomplexansandrelatedtaxa |