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MRP8/14 Is a Molecular Signature Triggered by Dopamine in HIV Latent Myeloid Targets That Increases HIV Transcription and Distinguishes HIV+ Methamphetamine Users with Detectable CSF Viral Load and Brain Pathology

There is a significant overlap between HIV infection and substance-use disorders. Dopamine (DA) is the most abundantly upregulated neurotransmitter in methamphetamine abuse, with receptors (DRD1-5) that are expressed by neurons as well as by a large diversity of cell types, including innate immune c...

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Detalles Bibliográficos
Autores principales: Basova, Liana V., Lindsey, Alexander, McGovern, Annemarie, Rosander, Ashley, Delorme-Walker, Violaine, ElShamy, Wael M., Pendyala, Ved Vasishtha, Gaskill, Peter Jesse, Ellis, Ronald J., Cherner, Mariana, Iudicello, Jennifer E., Marcondes, Maria Cecilia Garibaldi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304659/
https://www.ncbi.nlm.nih.gov/pubmed/37376663
http://dx.doi.org/10.3390/v15061363