Cargando…

MRP8/14 Is a Molecular Signature Triggered by Dopamine in HIV Latent Myeloid Targets That Increases HIV Transcription and Distinguishes HIV+ Methamphetamine Users with Detectable CSF Viral Load and Brain Pathology

There is a significant overlap between HIV infection and substance-use disorders. Dopamine (DA) is the most abundantly upregulated neurotransmitter in methamphetamine abuse, with receptors (DRD1-5) that are expressed by neurons as well as by a large diversity of cell types, including innate immune c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Basova, Liana V., Lindsey, Alexander, McGovern, Annemarie, Rosander, Ashley, Delorme-Walker, Violaine, ElShamy, Wael M., Pendyala, Ved Vasishtha, Gaskill, Peter Jesse, Ellis, Ronald J., Cherner, Mariana, Iudicello, Jennifer E., Marcondes, Maria Cecilia Garibaldi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304659/ https://www.ncbi.nlm.nih.gov/pubmed/37376663 http://dx.doi.org/10.3390/v15061363

Ejemplares similares

Detection of H3K4me3 Identifies NeuroHIV Signatures, Genomic Effects of Methamphetamine and Addiction Pathways in Postmortem HIV+ Brain Specimens that Are Not Amenable to Transcriptome Analysis
por: Basova, Liana, et al.
Publicado: (2021)

Polygenic networks in peripheral leukocytes indicate patterns associated with HIV infection and context-dependent effects of cannabis use
por: Basova, Liana V., et al.
Publicado: (2022)

The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition
por: Rogers, Jeffrey M., et al.
Publicado: (2023)

Systems Biology Analysis of the Antagonizing Effects of HIV-1 Tat Expression in the Brain over Transcriptional Changes Caused by Methamphetamine Sensitization
por: Basova, Liana V., et al.
Publicado: (2020)

Methamphetamine signals transcription of IL1β and TNFα in a reactive oxygen species-dependent manner and interacts with HIV-1 Tat to decrease antioxidant defense mechanisms
por: Basova, Liana V., et al.
Publicado: (2022)

Modeling the Function of TATA Box Binding Protein in Transcriptional Changes Induced by HIV-1 Tat in Innate Immune Cells and the Effect of Methamphetamine Exposure
por: Tjitro, Ryan, et al.
Publicado: (2019)

The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disorders
por: Mediouni, Sonia, et al.
Publicado: (2015)

Dopamine and its receptors play a role in the modulation of CCR5 expression in innate immune cells following exposure to Methamphetamine: Implications to HIV infection
por: Basova, Liana, et al.
Publicado: (2018)

Macrophages and brown adipocytes cross-communicate to modulate a thermogenic program following methamphetamine exposure
por: Sanchez-Alavez, Manuel, et al.
Publicado: (2020)

Reply to Augello, P.A.; Wu, J. Comment on “Rogers et al. The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition. Viruses 2023, 15, 674”
por: Rogers, Jeffrey M., et al.
Publicado: (2023)

Phenotypic changes in the brain of SIV-infected macaques exposed to methamphetamine parallel macrophage activation patterns induced by the common gamma-chain cytokine system
por: Bortell, Nikki, et al.
Publicado: (2015)

Recent cannabis use in HIV is associated with reduced inflammatory markers in CSF and blood
por: Ellis, Ronald J., et al.
Publicado: (2020)

Astrocyte-specific overexpressed gene signatures in response to methamphetamine exposure in vitro
por: Bortell, Nikki, et al.
Publicado: (2017)

Effects of HIV Infection, methamphetamine dependence and age on cortical thickness, area and volume
por: MacDuffie, Katherine E., et al.
Publicado: (2018)

Methamphetamine and Inflammatory Cytokines Increase Neuronal Na(+)/K(+)-ATPase Isoform 3: Relevance for HIV Associated Neurocognitive Disorders
por: Pendyala, Gurudutt, et al.
Publicado: (2012)

COMT Val158Met Polymorphism, Executive Dysfunction, and Sexual Risk Behavior in the Context of HIV Infection and Methamphetamine Dependence
por: Bousman, C. A., et al.
Publicado: (2010)

The Relationships between HIV-1 Infection, History of Methamphetamine Use Disorder, and Soluble Biomarkers in Blood and Cerebrospinal Fluid
por: Walter, T. Jordan, et al.
Publicado: (2021)

Novel RNA-Seq Signatures Post-Methamphetamine and Oxycodone Use in a Model of HIV-Associated Neurocognitive Disorders
por: Athota, Pranavi, et al.
Publicado: (2023)

Relationship of the balloon analog risk task to neurocognitive impairment differs by HIV serostatus and history of major depressive disorder
por: Saloner, Rowan, et al.
Publicado: (2022)

Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning
por: Bharti, Ajay R, et al.
Publicado: (2016)

HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads
por: Borgmann, Kathleen, et al.
Publicado: (2015)

Antiretroviral treatment and expression of the mRNA levels for Pgp, MRP1, MRP4 and MRP5 in HIV antiretroviral naïve patients. Follow-up at 48 weeks
por: Falasca, Francesca, et al.
Publicado: (2010)

Examining the Relationship Between HIV-Related Stigma and the Health and Wellbeing of Children and Adolescents Living with HIV: A Systematic Review
por: Robinson, Abbie, et al.
Publicado: (2023)

Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns
por: Basova, Liana V., et al.
Publicado: (2022)

Methamphetamine induces transcriptional changes in cultured HIV-infected mature monocytes that may contribute to HIV neuropathogenesis
por: Chilunda, Vanessa, et al.
Publicado: (2022)

Plasma biomarkers of vascular dysfunction uniquely relate to a vascular-risk profile of neurocognitive deficits in virally-suppressed adults with HIV
por: Saloner, Rowan, et al.
Publicado: (2022)

Plasma Proteomic Profiling in HIV-1 Infected Methamphetamine Abusers
por: Pottiez, Gwenael, et al.
Publicado: (2012)

Methamphetamine Dysregulates Macrophage Functions and Autophagy to Mediate HIV Neuropathogenesis
por: Barbaro, John M., et al.
Publicado: (2022)

In vivo effects of methamphetamine on brown fat reactive oxygen species and mitochondria
por: Bortell, Nikki, et al.
Publicado: (2015)

Methamphetamine augments HIV-1 gp120 inhibition of synaptic transmission and plasticity in rat hippocampal slices: Implications for methamphetamine exacerbation of HIV-associated neurocognitive disorders
por: Zheng, Ya, et al.
Publicado: (2022)

Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine
por: Turchan, Jadwiga, et al.
Publicado: (2001)

Epigenetic Alterations in the Brain Associated with HIV-1 Infection and Methamphetamine Dependence
por: Desplats, Paula, et al.
Publicado: (2014)

Colon dysregulation in methamphetamine self-administering HIV-1 transgenic rats
por: Persons, Amanda L., et al.
Publicado: (2018)

Double Jeopardy: Methamphetamine Use and HIV as Risk Factors for COVID-19
por: Carrico, Adam W., et al.
Publicado: (2020)

HIV Risk Profiles Among HIV-Positive, Methamphetamine-Using Men Who Have Sex with Both Men and Women
por: Nakamura, Nadine, et al.
Publicado: (2011)

Synergistic Impairment of the Neurovascular Unit by HIV-1 Infection and Methamphetamine Use: Implications for HIV-1-Associated Neurocognitive Disorders
por: Fattakhov, Nikolai, et al.
Publicado: (2021)

Proteomic and metabolomic strategies to investigate HIV-associated neurocognitive disorders
por: Pendyala, Gurudutt, et al.
Publicado: (2010)

As the HIV Epidemic among Young Women Grows, Can We Look to the SDGs to Reverse the Trend?
por: McGovern, Terry, et al.
Publicado: (2017)

Co-receptor signaling in the pathogenesis of neuroHIV
por: Nickoloff-Bybel, E. A., et al.
Publicado: (2021)

Using interviewer random effects to remove selection bias from HIV prevalence estimates
por: McGovern, Mark E, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_g1guvr4sfbkjoge1det45mc12m