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ABO-incompatible orthotopic heart transplant: a case report
Background: ABOi heart transplant has become routine for the majority of children <2 years old. An 8-month-old child with complex congenital heart disease presented to the Medical University of South Carolina Shawn Jenkins Children’s Hospital in need of transplantation. Methods: This case report...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
EDP Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304726/ https://www.ncbi.nlm.nih.gov/pubmed/37378443 http://dx.doi.org/10.1051/ject/2023009 |
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author | Strickland, Ashlyn Chianella, Dafne Andrea Kavarana, Minoo Savage, Andrew |
author_facet | Strickland, Ashlyn Chianella, Dafne Andrea Kavarana, Minoo Savage, Andrew |
author_sort | Strickland, Ashlyn |
collection | PubMed |
description | Background: ABOi heart transplant has become routine for the majority of children <2 years old. An 8-month-old child with complex congenital heart disease presented to the Medical University of South Carolina Shawn Jenkins Children’s Hospital in need of transplantation. Methods: This case report describes the use of ABOi transplantation and describes the details of the total exchange transfusion prior to cardiopulmonary bypass. Results: After a successful intraoperative total exchange transfusion following the ABOi protocol, the patient’s isohemagglutinin titers were 1 VC on postoperative day (POD) 1, and isohemagglutinin titer was <1 VC on POD 14. The patient had no signs of rejection and continued to recover. Conclusions: Successful ABOi transplantation requires planning, an interdisciplinary approach, and clear closed-loop communication. Planning with the surgical and anesthesia teams is necessary for the hemodynamic stability of the patient during the total volume exchange as well as precautions put in place to ensure the blood products used in this procedure are correct. Planning with the lab and blood bank is also necessary to ensure they are prepared with enough blood products and can run isohemagglutinin titers. |
format | Online Article Text |
id | pubmed-10304726 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | EDP Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-103047262023-06-29 ABO-incompatible orthotopic heart transplant: a case report Strickland, Ashlyn Chianella, Dafne Andrea Kavarana, Minoo Savage, Andrew J Extra Corpor Technol Case Report Background: ABOi heart transplant has become routine for the majority of children <2 years old. An 8-month-old child with complex congenital heart disease presented to the Medical University of South Carolina Shawn Jenkins Children’s Hospital in need of transplantation. Methods: This case report describes the use of ABOi transplantation and describes the details of the total exchange transfusion prior to cardiopulmonary bypass. Results: After a successful intraoperative total exchange transfusion following the ABOi protocol, the patient’s isohemagglutinin titers were 1 VC on postoperative day (POD) 1, and isohemagglutinin titer was <1 VC on POD 14. The patient had no signs of rejection and continued to recover. Conclusions: Successful ABOi transplantation requires planning, an interdisciplinary approach, and clear closed-loop communication. Planning with the surgical and anesthesia teams is necessary for the hemodynamic stability of the patient during the total volume exchange as well as precautions put in place to ensure the blood products used in this procedure are correct. Planning with the lab and blood bank is also necessary to ensure they are prepared with enough blood products and can run isohemagglutinin titers. EDP Sciences 2023-06-28 /pmc/articles/PMC10304726/ /pubmed/37378443 http://dx.doi.org/10.1051/ject/2023009 Text en © The Author(s), published by EDP Sciences, 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Strickland, Ashlyn Chianella, Dafne Andrea Kavarana, Minoo Savage, Andrew ABO-incompatible orthotopic heart transplant: a case report |
title | ABO-incompatible orthotopic heart transplant: a case report |
title_full | ABO-incompatible orthotopic heart transplant: a case report |
title_fullStr | ABO-incompatible orthotopic heart transplant: a case report |
title_full_unstemmed | ABO-incompatible orthotopic heart transplant: a case report |
title_short | ABO-incompatible orthotopic heart transplant: a case report |
title_sort | abo-incompatible orthotopic heart transplant: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304726/ https://www.ncbi.nlm.nih.gov/pubmed/37378443 http://dx.doi.org/10.1051/ject/2023009 |
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