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Identification of small-molecule inhibitors against the interaction of RNA-binding protein PSF and its target RNA for cancer treatment

Diverse cellular activities are modulated through a variety of RNAs, including long noncoding RNAs (lncRNAs), by binding to certain proteins. The inhibition of oncogenic proteins or RNAs is expected to suppress cancer cell proliferation. We have previously demonstrated that PSF interaction with its...

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Detalles Bibliográficos
Autores principales:	Takayama, Ken-ichi, Matsuoka, Seiji, Adachi, Shungo, Honma, Teruki, Yoshida, Masahito, Doi, Takayuki, Shin-ya, Kazuo, Yoshida, Minoru, Osada, Hiroyuki, Inoue, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Biological, Health, and Medical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304769/ https://www.ncbi.nlm.nih.gov/pubmed/37388923 http://dx.doi.org/10.1093/pnasnexus/pgad203

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