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Differential Confocal Optical Probes with Optimized Detection Efficiency and Pearson Correlation Coefficient Strategy Based on the Peak-Clustering Algorithm
Quantifying free-form surfaces using differential confocal microscopy can be challenging, as it requires balancing accuracy and efficiency. When the axial scanning mechanism involves sloshing and the measured surface has a finite slope, traditional linear fitting can introduce significant errors. Th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304892/ https://www.ncbi.nlm.nih.gov/pubmed/37374748 http://dx.doi.org/10.3390/mi14061163 |
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author | Wang, Zhiyi Wang, Tingyu Yang, Yongqiang Mi, Xiaotao Wang, Jianli |
author_facet | Wang, Zhiyi Wang, Tingyu Yang, Yongqiang Mi, Xiaotao Wang, Jianli |
author_sort | Wang, Zhiyi |
collection | PubMed |
description | Quantifying free-form surfaces using differential confocal microscopy can be challenging, as it requires balancing accuracy and efficiency. When the axial scanning mechanism involves sloshing and the measured surface has a finite slope, traditional linear fitting can introduce significant errors. This study introduces a compensation strategy based on Pearson’s correlation coefficient to effectively reduce measurement errors. Additionally, a fast-matching algorithm based on peak clustering was proposed to meet real-time requirements for non-contact probes. To validate the effectiveness of the compensation strategy and matching algorithm, detailed simulations and physical experiments were conducted. The results showed that for a numerical aperture of 0.4 and a depth of slope < 12°, the measurement error was <10 nm, improving the speed of the traditional algorithm system by 83.37%. Furthermore, repeatability and anti-disturbance experiments demonstrated that the proposed compensation strategy is simple, efficient, and robust. Overall, the proposed method has significant potential for application in the realization of high-speed measurements of free-form surfaces. |
format | Online Article Text |
id | pubmed-10304892 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103048922023-06-29 Differential Confocal Optical Probes with Optimized Detection Efficiency and Pearson Correlation Coefficient Strategy Based on the Peak-Clustering Algorithm Wang, Zhiyi Wang, Tingyu Yang, Yongqiang Mi, Xiaotao Wang, Jianli Micromachines (Basel) Article Quantifying free-form surfaces using differential confocal microscopy can be challenging, as it requires balancing accuracy and efficiency. When the axial scanning mechanism involves sloshing and the measured surface has a finite slope, traditional linear fitting can introduce significant errors. This study introduces a compensation strategy based on Pearson’s correlation coefficient to effectively reduce measurement errors. Additionally, a fast-matching algorithm based on peak clustering was proposed to meet real-time requirements for non-contact probes. To validate the effectiveness of the compensation strategy and matching algorithm, detailed simulations and physical experiments were conducted. The results showed that for a numerical aperture of 0.4 and a depth of slope < 12°, the measurement error was <10 nm, improving the speed of the traditional algorithm system by 83.37%. Furthermore, repeatability and anti-disturbance experiments demonstrated that the proposed compensation strategy is simple, efficient, and robust. Overall, the proposed method has significant potential for application in the realization of high-speed measurements of free-form surfaces. MDPI 2023-05-31 /pmc/articles/PMC10304892/ /pubmed/37374748 http://dx.doi.org/10.3390/mi14061163 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wang, Zhiyi Wang, Tingyu Yang, Yongqiang Mi, Xiaotao Wang, Jianli Differential Confocal Optical Probes with Optimized Detection Efficiency and Pearson Correlation Coefficient Strategy Based on the Peak-Clustering Algorithm |
title | Differential Confocal Optical Probes with Optimized Detection Efficiency and Pearson Correlation Coefficient Strategy Based on the Peak-Clustering Algorithm |
title_full | Differential Confocal Optical Probes with Optimized Detection Efficiency and Pearson Correlation Coefficient Strategy Based on the Peak-Clustering Algorithm |
title_fullStr | Differential Confocal Optical Probes with Optimized Detection Efficiency and Pearson Correlation Coefficient Strategy Based on the Peak-Clustering Algorithm |
title_full_unstemmed | Differential Confocal Optical Probes with Optimized Detection Efficiency and Pearson Correlation Coefficient Strategy Based on the Peak-Clustering Algorithm |
title_short | Differential Confocal Optical Probes with Optimized Detection Efficiency and Pearson Correlation Coefficient Strategy Based on the Peak-Clustering Algorithm |
title_sort | differential confocal optical probes with optimized detection efficiency and pearson correlation coefficient strategy based on the peak-clustering algorithm |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304892/ https://www.ncbi.nlm.nih.gov/pubmed/37374748 http://dx.doi.org/10.3390/mi14061163 |
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