Challenges and Strategies for Developing Recombinant Vaccines against Leptospirosis: Role of Expression Platforms and Adjuvants in Achieving Protective Efficacy

The first leptospiral recombinant vaccine was developed in the late 1990s. Since then, progress in the fields of reverse vaccinology (RV) and structural vaccinology (SV) has significantly improved the identification of novel surface-exposed and conserved vaccine targets. However, developing recombin...

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Detalles Bibliográficos
Autores principales: de Oliveira, Natasha Rodrigues, Santos, Francisco Denis Souza, dos Santos, Vitória Adrielly Catschor, Maia, Mara Andrade Colares, Oliveira, Thaís Larré, Dellagostin, Odir Antônio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305058/
https://www.ncbi.nlm.nih.gov/pubmed/37375478
http://dx.doi.org/10.3390/pathogens12060787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305058/
https://www.ncbi.nlm.nih.gov/pubmed/37375478
http://dx.doi.org/10.3390/pathogens12060787

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