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Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disorder marked by the death of dopaminergic neurons in the midbrain, the accumulation of α-synuclein aggregates, and motor deficits. A major contributor to dopaminergic neuronal loss is neuroinflammation. The inflammasome is a multiprotein complex tha...

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Detalles Bibliográficos
Autores principales: Cabrera Ranaldi, Erika d. l. R. M., Nuytemans, Karen, Martinez, Anisley, Luca, Corneliu C., Keane, Robert W., de Rivero Vaccari, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305113/
https://www.ncbi.nlm.nih.gov/pubmed/37375830
http://dx.doi.org/10.3390/ph16060883