Cargando…

Upregulation of Neuropilin-1 Inhibits HTLV-1 Infection

Infection with human T-cell leukemia virus type 1 (HTLV-1) can produce a spectrum of pathological effects ranging from inflammatory disorders to leukemia. In vivo, HTLV-1 predominantly infects CD4(+) T-cells. Infectious spread within this population involves the transfer of HTLV-1 virus particles fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kendle, Wesley, Hoang, Kimson, Korleski, Erica, Panfil, Amanda R., Polakowski, Nicholas, Lemasson, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305173/ https://www.ncbi.nlm.nih.gov/pubmed/37375521 http://dx.doi.org/10.3390/pathogens12060831

Ejemplares similares

HBZ upregulates myoferlin expression to facilitate HTLV-1 infection
por: Polakowski, Nicholas, et al.
Publicado: (2023)

HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I
por: Rushing, Amanda W., et al.
Publicado: (2019)

A BDNF/TrKB autocrine loop stimulated by HBZ is involved in HTLV-1-infected cell-survival
por: Polakowski, Nicholas, et al.
Publicado: (2014)

Direct Inhibition of RNAse T2 Expression by the HTLV-1 Viral Protein Tax
por: Polakowski, Nicholas, et al.
Publicado: (2011)

HTLV-1 Tax directly modulates expression of the CDK6 and RNASET2 genes
por: Polakowski, Nicholas, et al.
Publicado: (2011)

The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP
por: Wurm, Torsten, et al.
Publicado: (2012)

Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1
por: Wright, Diana G., et al.
Publicado: (2015)

Expression of a protein involved in bone resorption, Dkk1, is activated by HTLV-1 bZIP factor through its activation domain
por: Polakowski, Nicholas, et al.
Publicado: (2010)

Regulation of HTLV-1 transformation
por: Ernzen, Kyle J., et al.
Publicado: (2022)

Novel perspectives on antisense transcription in HIV-1, HTLV-1, and HTLV-2
por: Lin, Edward, et al.
Publicado: (2022)

PRMT5 Is Upregulated in HTLV-1-Mediated T-Cell Transformation and Selective Inhibition Alters Viral Gene Expression and Infected Cell Survival
por: Panfil, Amanda R., et al.
Publicado: (2015)

Functional comparison of the HTLV-1 and HTLV-2 antisense viral proteins: implications for pathogenesis
por: Panfil, Amanda R, et al.
Publicado: (2015)

Animal Models Utilized in HTLV-1 Research
por: Panfil, Amanda R, et al.
Publicado: (2013)

Inhibition of histone acetyltransferase (HAT) activity by HBZ extends beyond the p300/CBP HAT family
por: Wright, Diana G, et al.
Publicado: (2014)

CRISPR Genome Editing Applied to the Pathogenic Retrovirus HTLV-1
por: Panfil, Amanda R., et al.
Publicado: (2020)

Potential interference of HTLV-1 HBZ protein with the DNA damage response pathway
por: Wurm, Torsten, et al.
Publicado: (2011)

The Pleiotropic Effects of YBX1 on HTLV-1 Transcription
por: Smith, Susan, et al.
Publicado: (2023)

HBZ inhibits the HAT activity of the cellular coactivators p300 and CBP
por: Wright, Diana, et al.
Publicado: (2011)

Prognostic implication of neuropilin-1 upregulation in human nasopharyngeal carcinoma
por: Xu, Yu, et al.
Publicado: (2013)

JunD/HBZ enhances HBZ enhances HTLV-1 antisense transcription
por: Peloponese, Jean-Marie, et al.
Publicado: (2011)

HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo
por: Martinez, Michael P., et al.
Publicado: (2019)

Role of protein arginine methyltransferase 5 over-expression in HTLV-1-driven cellular transformation and leukemia
por: Panfil, Amanda R, et al.
Publicado: (2014)

Role of protein arginine methyltransferase 5 over-expression in HTLV-1-driven cellular transformation and leukemia
por: Panfil, Amanda R, et al.
Publicado: (2015)

Activation of the aryl hydrocarbon receptor inhibits neuropilin-1 upregulation on IL-2-responding CD4(+) T cells
por: Sandoval, Simone, et al.
Publicado: (2023)

The PRMT5 inhibitor EPZ015666 is effective against HTLV-1-transformed T-cell lines in vitro and in vivo
por: Ernzen, Kyle, et al.
Publicado: (2023)

Neuropilin-1 is upregulated by Wnt/β-catenin signaling and is important for mammary stem cells
por: Liu, Wei, et al.
Publicado: (2017)

Crystal Structure of the Neuropilin-1 MAM Domain: Completing the Neuropilin-1 Ectodomain Picture
por: Yelland, Tamas, et al.
Publicado: (2016)

Stability of the HTLV-1 Antisense-Derived Protein, HBZ, Is Regulated by the E3 Ubiquitin-Protein Ligase, UBR5
por: Panfil, Amanda R., et al.
Publicado: (2018)

Neuropilin-1 in Transplantation Tolerance
por: Campos-Mora, Mauricio, et al.
Publicado: (2013)

Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma
por: Dumond, Aurore, et al.
Publicado: (2021)

Distinct Roles for Neuropilin1 and Neuropilin2 during Mouse Corneal Innervation
por: McKenna, Chelsey C., et al.
Publicado: (2012)

Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis
por: Benwell, Christopher J., et al.
Publicado: (2022)

HTLV-1 intragenic viral enhancer influences immortalization phenotype in vitro, but is dispensable for persistence and disease development in animal models
por: Maksimova, Victoria, et al.
Publicado: (2022)

HTLV-1 Hbz protein, but not hbz mRNA secondary structure, is critical for viral persistence and disease development
por: Maksimova, Victoria, et al.
Publicado: (2023)

Biochemical Characterization, Specificity and Inhibition Studies of HTLV-1, HTLV-2, and HTLV-3 Proteases
por: Kassay, Norbert, et al.
Publicado: (2021)

Induction of galectin-1 expression by HTLV-I Tax and its impact on HTLV-I infectivity
por: Gauthier, Sonia, et al.
Publicado: (2008)

HTLV-1 clonality in adult T-cell leukaemia and non-malignant HTLV-1 infection
por: Bangham, Charles R.M., et al.
Publicado: (2014)

HTLV-1 and Co-infections
por: Rosadas, Carolina, et al.
Publicado: (2022)

Role of Neuropilin-1 in Diabetic Nephropathy
por: Bondeva, Tzvetanka, et al.
Publicado: (2015)

The role of Neuropilin-1 in COVID-19
por: Mayi, Bindu S., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_eiim8sp2s6ng27a2ie6f5fk8l1