The Alternating Access Mechanism in Mammalian Multidrug Resistance Transporters and Their Bacterial Homologs

Multidrug resistance (MDR) proteins belonging to the ATP-Binding Cassette (ABC) transporter group play a crucial role in the export of cytotoxic drugs across cell membranes. These proteins are particularly fascinating due to their ability to confer drug resistance, which subsequently leads to the fa...

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Detalles Bibliográficos
Autores principales: Badiee, Shadi A, Isu, Ugochi H., Khodadadi, Ehsaneh, Moradi, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305233/
https://www.ncbi.nlm.nih.gov/pubmed/37367772
http://dx.doi.org/10.3390/membranes13060568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305233/
https://www.ncbi.nlm.nih.gov/pubmed/37367772
http://dx.doi.org/10.3390/membranes13060568

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