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Geranylgeraniol Application in Human Osteoblasts and Osteoclasts for Reversal of the Effect of Bisphosphonates

Nitrogen-containing bisphosphonates lead to the depletion of geranylgeranyl pyrophosphate involved in the mevalonate pathway. The effect of geranylgeraniol (GGOH) on human osteoblast and osteoclast activities suppressed by zoledronate was investigated in this study. The effect of GGOH on human osteo...

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Detalles Bibliográficos
Autores principales:	Jung, Junho, Park, Jung Soo, Chun, Jeewan, Al-Nawas, Bilal, Ziebart, Thomas, Kwon, Yong-Dae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305301/ https://www.ncbi.nlm.nih.gov/pubmed/37374134 http://dx.doi.org/10.3390/life13061353

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