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Structural Model for Factor X Inhibition of IgM and Complement-Mediated Neutralization of Adenovirus
Adenovirus has strong therapeutic potential as an oncolytic virus and gene therapy vector. However, injecting human species C serotype 5 adenovirus, HAdv-C5, into the bloodstream leads to numerous interactions with plasma proteins that affect viral tropism and biodistribution, and can lead to potent...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305487/ https://www.ncbi.nlm.nih.gov/pubmed/37376642 http://dx.doi.org/10.3390/v15061343 |