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A Chemically Defined TLR3 Agonist with Anticancer Activity

Toll-like receptor 3 (TLR3) agonists such as polyinosinic:polycytidylic acid (poly(I:C)) have immunostimulatory effects that can be taken advantage of to induce anticancer immune responses in preclinical models. In addition, poly(I:C) has been introduced into clinical trials to demonstrate its effic...

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Detalles Bibliográficos
Autores principales: Le Naour, Julie, Thierry, Sylvain, Scuderi, Sarah Adriana, Boucard-Jourdin, Mathilde, Liu, Peng, Bonnin, Marc, Pan, Yuhong, Perret, Clémence, Zhao, Liwei, Mao, Misha, Renoux, Chloé, Pérez-Lanzón, María, Martin, Baptiste, Kepp, Oliver, Kroemer, Guido, Werlé, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305499/
https://www.ncbi.nlm.nih.gov/pubmed/37389102
http://dx.doi.org/10.1080/2162402X.2023.2227510