Cargando…

Antiretroviral therapy abandonment among adolescents and young people with HIV/AIDS during COVID-19: A case-control study

OBJECTIVE: to identify the factors associated with antiretroviral therapy abandonment among adolescents and young people living with HIV/AIDS during the COVID-19 pandemic. METHOD: a case-control study carried out between 2020 and 2021 in Maringá, Paraná. The cases corresponded to the following: adol...

Descripción completa

Detalles Bibliográficos
Autores principales: Piran, Camila Moraes Garollo, Cargnin, Alana Vitória Escritori, Shibukawa, Bianca Machado Cruz, de Oliveira, Natan Nascimento, da Silva, Marcelo, Furtado, Marcela Demitto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306057/
https://www.ncbi.nlm.nih.gov/pubmed/37341259
http://dx.doi.org/10.1590/1518-8345.6497.3947
_version_ 1785065859026255872
author Piran, Camila Moraes Garollo
Cargnin, Alana Vitória Escritori
Shibukawa, Bianca Machado Cruz
de Oliveira, Natan Nascimento
da Silva, Marcelo
Furtado, Marcela Demitto
author_facet Piran, Camila Moraes Garollo
Cargnin, Alana Vitória Escritori
Shibukawa, Bianca Machado Cruz
de Oliveira, Natan Nascimento
da Silva, Marcelo
Furtado, Marcela Demitto
author_sort Piran, Camila Moraes Garollo
collection PubMed
description OBJECTIVE: to identify the factors associated with antiretroviral therapy abandonment among adolescents and young people living with HIV/AIDS during the COVID-19 pandemic. METHOD: a case-control study carried out between 2020 and 2021 in Maringá, Paraná. The cases corresponded to the following: adolescents and young people (aged from 10 to 24 years old) diagnosed with HIV/AIDS and who abandoned treatment, while the Control Group consisted of people with similar sociodemographic characteristics, diagnosed with HIV/AIDS and with no history of treatment abandonment. Pairing of the cases and controls was by convenience, with four controls for each case. The research instrument presented sociodemographic variables, clinical characteristics and others, whose association with treatment abandonment was analyzed by means of logistic regression. RESULTS: a total of 27 cases and 109 controls were included in the study (1/4 ratio). The variable associated with an increased chance of abandonment was age close to 22.8 years old (OR(adj): 1.47; 95% CI: 1.07-2.13; p=0.024). Sporadic condom use (OR(adj): 0.22; 95% CI: 0.07-0.59; p=0.003) and having an opportunistic infection (OR: 0.31; 95% CI: 0.10-0.90; p=0.030) were protective factors. CONCLUSION: age close to 23 years old at the last consultation was associated with antiretroviral therapy abandonment. The presence of opportunistic infections and condom use are determining factors for treatment continuity during COVID-19.
format Online
Article
Text
id pubmed-10306057
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo
record_format MEDLINE/PubMed
spelling pubmed-103060572023-06-29 Antiretroviral therapy abandonment among adolescents and young people with HIV/AIDS during COVID-19: A case-control study Piran, Camila Moraes Garollo Cargnin, Alana Vitória Escritori Shibukawa, Bianca Machado Cruz de Oliveira, Natan Nascimento da Silva, Marcelo Furtado, Marcela Demitto Rev Lat Am Enfermagem Artículo Original OBJECTIVE: to identify the factors associated with antiretroviral therapy abandonment among adolescents and young people living with HIV/AIDS during the COVID-19 pandemic. METHOD: a case-control study carried out between 2020 and 2021 in Maringá, Paraná. The cases corresponded to the following: adolescents and young people (aged from 10 to 24 years old) diagnosed with HIV/AIDS and who abandoned treatment, while the Control Group consisted of people with similar sociodemographic characteristics, diagnosed with HIV/AIDS and with no history of treatment abandonment. Pairing of the cases and controls was by convenience, with four controls for each case. The research instrument presented sociodemographic variables, clinical characteristics and others, whose association with treatment abandonment was analyzed by means of logistic regression. RESULTS: a total of 27 cases and 109 controls were included in the study (1/4 ratio). The variable associated with an increased chance of abandonment was age close to 22.8 years old (OR(adj): 1.47; 95% CI: 1.07-2.13; p=0.024). Sporadic condom use (OR(adj): 0.22; 95% CI: 0.07-0.59; p=0.003) and having an opportunistic infection (OR: 0.31; 95% CI: 0.10-0.90; p=0.030) were protective factors. CONCLUSION: age close to 23 years old at the last consultation was associated with antiretroviral therapy abandonment. The presence of opportunistic infections and condom use are determining factors for treatment continuity during COVID-19. Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2023-06-19 /pmc/articles/PMC10306057/ /pubmed/37341259 http://dx.doi.org/10.1590/1518-8345.6497.3947 Text en Esta licencia permite a otros distribuir, mezclar, ajustar y construir a partir de su obra, incluso con fines comerciales, siempre que le sea reconocida la autoría de la creación original. Esta es la licencia más servicial de las ofrecidas. Recomendada para una máxima difusión y utilización de los materiales sujetos a la licencia. https://creativecommons.org/licenses/by/4.0/Este es un artículo de acceso abierto distribuido bajo los términos de la Licencia Creative Commons CC BY.
spellingShingle Artículo Original
Piran, Camila Moraes Garollo
Cargnin, Alana Vitória Escritori
Shibukawa, Bianca Machado Cruz
de Oliveira, Natan Nascimento
da Silva, Marcelo
Furtado, Marcela Demitto
Antiretroviral therapy abandonment among adolescents and young people with HIV/AIDS during COVID-19: A case-control study
title Antiretroviral therapy abandonment among adolescents and young people with HIV/AIDS during COVID-19: A case-control study
title_full Antiretroviral therapy abandonment among adolescents and young people with HIV/AIDS during COVID-19: A case-control study
title_fullStr Antiretroviral therapy abandonment among adolescents and young people with HIV/AIDS during COVID-19: A case-control study
title_full_unstemmed Antiretroviral therapy abandonment among adolescents and young people with HIV/AIDS during COVID-19: A case-control study
title_short Antiretroviral therapy abandonment among adolescents and young people with HIV/AIDS during COVID-19: A case-control study
title_sort antiretroviral therapy abandonment among adolescents and young people with hiv/aids during covid-19: a case-control study
topic Artículo Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306057/
https://www.ncbi.nlm.nih.gov/pubmed/37341259
http://dx.doi.org/10.1590/1518-8345.6497.3947
work_keys_str_mv AT pirancamilamoraesgarollo antiretroviraltherapyabandonmentamongadolescentsandyoungpeoplewithhivaidsduringcovid19acasecontrolstudy
AT cargninalanavitoriaescritori antiretroviraltherapyabandonmentamongadolescentsandyoungpeoplewithhivaidsduringcovid19acasecontrolstudy
AT shibukawabiancamachadocruz antiretroviraltherapyabandonmentamongadolescentsandyoungpeoplewithhivaidsduringcovid19acasecontrolstudy
AT deoliveiranatannascimento antiretroviraltherapyabandonmentamongadolescentsandyoungpeoplewithhivaidsduringcovid19acasecontrolstudy
AT dasilvamarcelo antiretroviraltherapyabandonmentamongadolescentsandyoungpeoplewithhivaidsduringcovid19acasecontrolstudy
AT furtadomarcelademitto antiretroviraltherapyabandonmentamongadolescentsandyoungpeoplewithhivaidsduringcovid19acasecontrolstudy