Activation of the cGAS-STING pathway by a mitochondrial DNA-targeted emissive rhodium(iii) metallointercalator

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon (STING) pathway is a key mediator of innate immunity involved in cancer development and treatment. The roles of mitochondrial DNA (mtDNA) in cancer immunotherapy have gradually emerged. Herein, we report a highly emissive rhodium(iii) compl...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Yue, Chen, Xiao-Xiao, Zhang, Dong-Yang, Wang, Wen-Jin, Peng, Kun, Li, Zhi-Yuan, Mao, Zong-Wan, Tan, Cai-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306090/
https://www.ncbi.nlm.nih.gov/pubmed/37389261
http://dx.doi.org/10.1039/d3sc01737k

Ejemplares similares

Ejemplares similares