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Neurostimulation for Spinal Lesions: Enhancing Recovery and Axonal Regeneration

Spinal neurostimulation is a promising approach for treating spinal lesions and has implications in various neurological disorders. It promotes axonal regeneration and neuronal plasticity to reestablish disrupted signal transduction pathways following spinal injuries or degeneration. This paper revi...

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Autores principales: Patel, Drashti, Benjamin, Jonathan, Patel, Aashay, Fleeting, Chance, Casauay, Jed, Foreman, Marco, Sheth, Sohum, Lucke-Wold, Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306172/
https://www.ncbi.nlm.nih.gov/pubmed/37384035
http://dx.doi.org/10.52916/jmrs234107
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author Patel, Drashti
Benjamin, Jonathan
Patel, Aashay
Fleeting, Chance
Casauay, Jed
Foreman, Marco
Sheth, Sohum
Lucke-Wold, Brandon
author_facet Patel, Drashti
Benjamin, Jonathan
Patel, Aashay
Fleeting, Chance
Casauay, Jed
Foreman, Marco
Sheth, Sohum
Lucke-Wold, Brandon
author_sort Patel, Drashti
collection PubMed
description Spinal neurostimulation is a promising approach for treating spinal lesions and has implications in various neurological disorders. It promotes axonal regeneration and neuronal plasticity to reestablish disrupted signal transduction pathways following spinal injuries or degeneration. This paper reviews the current technology and its differing utilities in various types of neurostimulation, including invasive and noninvasive methods. The paper also explores the efficacy of spinal compression and decompression therapy, with a primary focus on degenerative spinal disorders. Moreover, the potential of spinal neurostimulation in therapies for motor disorders, such as Parkinson’s disease and demyelinating disorders, is discussed. Finally, the paper examines the changing guidelines of use for spinal neurostimulation following surgical tumor resection. The review suggests that spinal neurostimulation is a promising therapy for axonal regeneration in spinal lesions. This paper concludes that future research should focus on the long-term effects and safety of these existing technologies, optimizing the use of spinal neurostimulation to enhance recovery and exploring its potential for other neurological disorders.
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spelling pubmed-103061722023-06-28 Neurostimulation for Spinal Lesions: Enhancing Recovery and Axonal Regeneration Patel, Drashti Benjamin, Jonathan Patel, Aashay Fleeting, Chance Casauay, Jed Foreman, Marco Sheth, Sohum Lucke-Wold, Brandon J Med Res Surg Article Spinal neurostimulation is a promising approach for treating spinal lesions and has implications in various neurological disorders. It promotes axonal regeneration and neuronal plasticity to reestablish disrupted signal transduction pathways following spinal injuries or degeneration. This paper reviews the current technology and its differing utilities in various types of neurostimulation, including invasive and noninvasive methods. The paper also explores the efficacy of spinal compression and decompression therapy, with a primary focus on degenerative spinal disorders. Moreover, the potential of spinal neurostimulation in therapies for motor disorders, such as Parkinson’s disease and demyelinating disorders, is discussed. Finally, the paper examines the changing guidelines of use for spinal neurostimulation following surgical tumor resection. The review suggests that spinal neurostimulation is a promising therapy for axonal regeneration in spinal lesions. This paper concludes that future research should focus on the long-term effects and safety of these existing technologies, optimizing the use of spinal neurostimulation to enhance recovery and exploring its potential for other neurological disorders. 2023-06 2023-06-03 /pmc/articles/PMC10306172/ /pubmed/37384035 http://dx.doi.org/10.52916/jmrs234107 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Patel, Drashti
Benjamin, Jonathan
Patel, Aashay
Fleeting, Chance
Casauay, Jed
Foreman, Marco
Sheth, Sohum
Lucke-Wold, Brandon
Neurostimulation for Spinal Lesions: Enhancing Recovery and Axonal Regeneration
title Neurostimulation for Spinal Lesions: Enhancing Recovery and Axonal Regeneration
title_full Neurostimulation for Spinal Lesions: Enhancing Recovery and Axonal Regeneration
title_fullStr Neurostimulation for Spinal Lesions: Enhancing Recovery and Axonal Regeneration
title_full_unstemmed Neurostimulation for Spinal Lesions: Enhancing Recovery and Axonal Regeneration
title_short Neurostimulation for Spinal Lesions: Enhancing Recovery and Axonal Regeneration
title_sort neurostimulation for spinal lesions: enhancing recovery and axonal regeneration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306172/
https://www.ncbi.nlm.nih.gov/pubmed/37384035
http://dx.doi.org/10.52916/jmrs234107
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