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Autophagy prevents early proinflammatory responses and neutrophil recruitment during Mycobacterium tuberculosis infection without affecting pathogen burden in macrophages

The immune response to Mycobacterium tuberculosis infection determines tuberculosis disease outcomes, yet we have an incomplete understanding of what immune factors contribute to a protective immune response. Neutrophilic inflammation has been associated with poor disease prognosis in humans and in...

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Detalles Bibliográficos
Autores principales: Kinsella, Rachel L., Kimmey, Jacqueline M., Smirnov, Asya, Woodson, Reilly, Gaggioli, Margaret R., Chavez, Sthefany M., Kreamalmeyer, Darren, Stallings, Christina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306192/
https://www.ncbi.nlm.nih.gov/pubmed/37319285
http://dx.doi.org/10.1371/journal.pbio.3002159