Cargando…

Chronic Semaglutide Treatment in Rats Leads to Daily Excessive Concentration-Dependent Sucrose Intake

CONTEXT: The glucagon-like peptide-1 receptor (GLP-1R) agonist semaglutide (SEMA) produces 15% weight loss when chronically administered to humans with obesity. METHODS: In 2 separate experiments, rats received daily injections of either vehicle (VEH) or SEMA starting at 7 µg/kg body weight (BW) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cawthon, Carolina R, Blonde, Ginger D, Nisi, A Valentina, Bloomston, Haley M, Krubitski, Belle, le Roux, Carel W, Spector, Alan C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306276/ https://www.ncbi.nlm.nih.gov/pubmed/37388574 http://dx.doi.org/10.1210/jendso/bvad074

Ejemplares similares

The Influence of Roux-en-Y Gastric Bypass and Diet on NaCl and Sucrose Taste Detection Thresholds and Number of Circumvallate and Fungiform Taste Buds in Female Rats
por: Hyde, Kellie M., et al.
Publicado: (2022)

Extensive Gustatory Cortex Lesions Significantly Impair Taste Sensitivity to KCl and Quinine but Not to Sucrose in Rats
por: Bales, Michelle B., et al.
Publicado: (2015)

Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery
por: Blonde, Ginger D., et al.
Publicado: (2021)

Gastric Bypass in Rats Does Not Decrease Appetitive Behavior Towards Sweet or Fatty Fluids Despite Blunting Preferential Intake of Sugar and Fat
por: Mathes, Clare M., et al.
Publicado: (2015)

Concurrent and Delayed Behavioral and Monoamine Alterations by Excessive Sucrose Intake in Juvenile Mice
por: Choe, Won-Hui, et al.
Publicado: (2020)

The Impact Once-Weekly Semaglutide 2.4 mg Will Have on Clinical Practice: A Focus on the STEP Trials
por: Alabduljabbar, Khaled, et al.
Publicado: (2022)

Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised controlled clinical trial
por: McCrimmon, Rory J., et al.
Publicado: (2020)

A new era for oral peptides: SNAC and the development of oral semaglutide for the treatment of type 2 diabetes
por: Aroda, Vanita R., et al.
Publicado: (2022)

Semaglutide Treatment of Excessive Body Weight in Obese PCOS Patients Unresponsive to Lifestyle Programs
por: Carmina, Enrico, et al.
Publicado: (2023)

Urinary Erythritol Is Increased in Response to Excess Dietary Sucrose
por: Ortiz, Semira, et al.
Publicado: (2022)

Extensive Lesions in Rat Insular Cortex Significantly Disrupt Taste Sensitivity to NaCl and KCl and Slow Salt Discrimination Learning
por: Blonde, Ginger D., et al.
Publicado: (2015)

Peroxisome Proliferator-Activated Receptor α Has a Protective Effect on Fatty Liver Caused by Excessive Sucrose Intake
por: Yamazaki, Tomomi, et al.
Publicado: (2022)

Oral Semaglutide
por: Bui, Vinh, et al.
Publicado: (2018)

Safety of Semaglutide
por: Smits, Mark M., et al.
Publicado: (2021)

Exploring the Contribution of Autophagy to the Excess-Sucrose Response in Arabidopsis thaliana
por: Laloum, Daniel, et al.
Publicado: (2022)

Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats
por: Aranäs, Cajsa, et al.
Publicado: (2023)

Antismoking agents do not contribute synergistically to semaglutide’s ability to reduce alcohol intake in rats
por: Aranäs, Cajsa, et al.
Publicado: (2023)

Corrigendum: Safety of Semaglutide
por: Smits, Mark M., et al.
Publicado: (2021)

Excess sucrose intake during pregnancy programs fetal brain glucocorticoid receptor expression in female but not male C57Bl/6J mice
por: Kulhanek, Debra, et al.
Publicado: (2021)

The Discovery and Development of Liraglutide and Semaglutide
por: Knudsen, Lotte Bjerre, et al.
Publicado: (2019)

Semaglutide for type 2 diabetes
Publicado: (2020)

Semaglutide-associated bullous pemphigoid
por: Burruss, Clayton P., et al.
Publicado: (2021)

Semaglutide-eye-catching results
por: Cigrovski Berkovic, Maja, et al.
Publicado: (2023)

Emerging Anesthesia Risks with Semaglutide
por: Fezza, Reed, et al.
Publicado: (2023)

Efficacy, safety and cardiovascular outcomes of once‐daily oral semaglutide in patients with type 2 diabetes: The PIONEER programme
por: Thethi, Tina K., et al.
Publicado: (2020)

Changes in Glucose Metabolism and Glycemic Status With Once-Weekly Subcutaneous Semaglutide 2.4 mg Among Participants With Prediabetes in the STEP Program
por: Perreault, Leigh, et al.
Publicado: (2022)

Once-weekly Subcutaneous Semaglutide 2.4 mg Reduces Body Weight in Adults with Overweight or Obesity Regardless of Baseline Characteristics (STEP 1)
por: Kushner, Robert F, et al.
Publicado: (2021)

A compulsive act of excess water intake leading to hyponatraemia and rhabdomyolysis: a case report
por: Fernando, Sudheera, et al.
Publicado: (2019)

Excessive Sodium Intake Leads to Cardiovascular Disease by Promoting Sex-Specific Dysfunction of Murine Heart
por: Chen, Xiuli, et al.
Publicado: (2022)

Different Effects of Once-weekly and Once-daily Administered GLP-1RA Semaglutide and Liraglutide on Bile Acid Diarrhea
por: Kårhus, Martin Lund, et al.
Publicado: (2022)

Clinically-Relevant Weight Loss is Achieved Independently of Early Weight Loss Response to Once-Weekly Subcutaneous Semaglutide 2.4 MG (STEP 4)
por: Mosenzon, Ofri, et al.
Publicado: (2021)

Efficacy of salt reduction for managing overactive bladder symptoms: a prospective study in patients with excessive daily salt intake
por: Matsuo, Tomohiro, et al.
Publicado: (2021)

Acute Kidney Injury Associated With Semaglutide
por: Leehey, David J., et al.
Publicado: (2021)

Oral Semaglutide: Dosage in Special Situations
por: Kalra, Sanjay, et al.
Publicado: (2022)

Semaglutide in Obesity: Unmet Needs in Men
por: Jensterle, Mojca, et al.
Publicado: (2023)

Time-restricted feeding suppresses excess sucrose-induced plasma and liver lipid accumulation in rats
por: Sun, Shumin, et al.
Publicado: (2018)

Hypercaloric diet models do not develop heart failure, but the excess sucrose promotes contractility dysfunction
por: Martins Matias, Amanda, et al.
Publicado: (2020)

Reasons for raising the maximum acceptable daily intake of EDTA and the benefits for iron fortification of foods for children 6–24 months of age
por: Wreesmann, Carel Theo Jozef
Publicado: (2014)

Effect of Diet on Preference and Intake of Sucrose in Obese Prone and Resistant Rats
por: Duca, Frank A., et al.
Publicado: (2014)

Fructose and Sucrose Intake Increase Exogenous Carbohydrate Oxidation during Exercise
por: Trommelen, Jorn, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1kl7r986796ubbq7peaath2bfg