Functional regulation of an intrinsically disordered protein via a conformationally excited state

A longstanding goal in the field of intrinsically disordered proteins (IDPs) is to characterize their structural heterogeneity and pinpoint the role of this heterogeneity in IDP function. Here, we use multinuclear chemical exchange saturation (CEST) nuclear magnetic resonance to determine the struct...

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Detalles Bibliográficos
Autores principales: Madhurima, Kulkarni, Nandi, Bodhisatwa, Munshi, Sneha, Naganathan, Athi N., Sekhar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306299/
https://www.ncbi.nlm.nih.gov/pubmed/37379390
http://dx.doi.org/10.1126/sciadv.adh4591

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