Antiviral activity of singlet oxygen-photogenerating perylene compounds against SARS-CoV-2: Interaction with the viral envelope and photodynamic virion inactivation

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has prompted great interest in novel broad-spectrum antivirals, including perylene-related compounds. In the present study, we performed a structure–activity relationship analysi...

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Detalles Bibliográficos
Autores principales: Straková, Petra, Bednář, Petr, Kotouček, Jan, Holoubek, Jiří, Fořtová, Andrea, Svoboda, Pavel, Štefánik, Michal, Huvarová, Ivana, Šimečková, Pavlína, Mašek, Josef, Gvozdev, Daniil A., Mikhnovets, Igor E., Chistov, Alexey A., Nikitin, Timofei D., Krasilnikov, Maxim S., Ustinov, Alexey V., Alferova, Vera A., Korshun, Vladimir A., Růžek, Daniel, Eyer, Luděk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307035/
https://www.ncbi.nlm.nih.gov/pubmed/37339718
http://dx.doi.org/10.1016/j.virusres.2023.199158

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