Marine Algae Extract (Grateloupia Sparsa) for the Green Synthesis of Co(3)O(4)NPs: Antioxidant, Antibacterial, Anticancer, and Hemolytic Activities

The aqueous extract of red algae was used for bio-inspired manufacturing of cobalt oxide nanoparticles (Co(3)O(4)NPs) and for antioxidant, antibacterial, hemolytic potency, and anticancer activity. Typical, characterization techniques include UV-Vis, SEM, EDAX, TEM, FTIR, XRD, and TGA. Using an X-ray diffraction assay, the size of the Co(3)O(4)NPs crystal was determined to range from 23.2 to 11.8 nm. Based on TEM and SEM pictures, biosynthesized Co(3)O(4)NPs' had a homogeneous spherical morphology with a 28.8 to 7.6 nm average diameter. Furthermore, Co(3)O(4)NPs biological properties were investigated, including determining the antibacterial potency using the zone of inhibition (ZOI) method and determining the minimal inhibitory concentration (MIC). The antibacterial activity of Co(3)O(4)NPs was higher than that of the ciprofloxacin standard. Alternatively, scavenging of DPPH free radical investigation was carried out to test the antioxidant capacitance of Co(3)O(4)NPs, revealing significant antioxidant ability. The biosynthesized Co(3)O(4)NPs have a dose-dependent effect on erythrocyte viability, indicating that this technique is harmless. Furthermore, bioinspired Co(3)O(4)NPs effectively against HepG2 cancer cells (IC(50): 201.3 μg/ml). Co(3)O(4)NPs would be a therapeutic aid due to their antioxidant, antibacterial, and anticancer properties.