Defining blood-induced microglia functions in neurodegeneration through multiomic profiling

Blood protein extravasation through a disrupted blood–brain barrier and innate immune activation are hallmarks of neurological diseases and emerging therapeutic targets. However, how blood proteins polarize innate immune cells remains largely unknown. Here, we established an unbiased blood-innate im...

Descripción completa

Detalles Bibliográficos
Autores principales: Mendiola, Andrew S., Yan, Zhaoqi, Dixit, Karuna, Johnson, Jeffrey R., Bouhaddou, Mehdi, Meyer-Franke, Anke, Shin, Min-Gyoung, Yong, Yu, Agrawal, Ayushi, MacDonald, Eilidh, Muthukumar, Gayathri, Pearce, Clairice, Arun, Nikhita, Cabriga, Belinda, Meza-Acevedo, Rosa, Alzamora, Maria del Pilar S., Zamvil, Scott S., Pico, Alexander R., Ryu, Jae Kyu, Krogan, Nevan J., Akassoglou, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307624/
https://www.ncbi.nlm.nih.gov/pubmed/37291385
http://dx.doi.org/10.1038/s41590-023-01522-0

Ejemplares similares

Ejemplares similares