ERα-associated translocations underlie oncogene amplifications in breast cancer

Focal copy-number amplification is an oncogenic event. Although recent studies have revealed the complex structure(1–3) and the evolutionary trajectories(4) of oncogene amplicons, their origin remains poorly understood. Here we show that focal amplifications in breast cancer frequently derive from a...

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Detalles Bibliográficos
Autores principales: Lee, Jake June-Koo, Jung, Youngsook Lucy, Cheong, Taek-Chin, Espejo Valle-Inclan, Jose, Chu, Chong, Gulhan, Doga C., Ljungström, Viktor, Jin, Hu, Viswanadham, Vinayak V., Watson, Emma V., Cortés-Ciriano, Isidro, Elledge, Stephen J., Chiarle, Roberto, Pellman, David, Park, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307628/
https://www.ncbi.nlm.nih.gov/pubmed/37198482
http://dx.doi.org/10.1038/s41586-023-06057-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307628/
https://www.ncbi.nlm.nih.gov/pubmed/37198482
http://dx.doi.org/10.1038/s41586-023-06057-w

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