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ERα-associated translocations underlie oncogene amplifications in breast cancer
Focal copy-number amplification is an oncogenic event. Although recent studies have revealed the complex structure(1–3) and the evolutionary trajectories(4) of oncogene amplicons, their origin remains poorly understood. Here we show that focal amplifications in breast cancer frequently derive from a...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307628/ https://www.ncbi.nlm.nih.gov/pubmed/37198482 http://dx.doi.org/10.1038/s41586-023-06057-w |