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Developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in Ghanaian homes
Globally Antimicrobial Resistance (AMR) constitutes a health crisis, particularly in developing countries, where infectious disease are commonly fatal. There is clear evidence for microbial exposure and infection transmission within the home. Personal and environmental hygiene are the best ways of r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307869/ https://www.ncbi.nlm.nih.gov/pubmed/37380793 http://dx.doi.org/10.1038/s41598-023-37317-4 |
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author | Tsekleves, Emmanuel de Souza, Dziedzom Pickup, Roger Ahorlu, Collins Darby, Andy |
author_facet | Tsekleves, Emmanuel de Souza, Dziedzom Pickup, Roger Ahorlu, Collins Darby, Andy |
author_sort | Tsekleves, Emmanuel |
collection | PubMed |
description | Globally Antimicrobial Resistance (AMR) constitutes a health crisis, particularly in developing countries, where infectious disease are commonly fatal. There is clear evidence for microbial exposure and infection transmission within the home. Personal and environmental hygiene are the best ways of reducing household infections thus decreasing the need for antibiotics and consequently diminishing AMR. Despite this being an obvious step, research efforts to understand the home environment and its impact on AMR, cleaning and possible interventions on household cleaning are limited. We combined design and microbiology methods in an innovative mixed-method approach. A traditional survey design (n = 240), a design ethnography (n = 12), a co-design workshop and a pre-intervention microbiological dust sample analysis was undertaken to provide insights for codesign workshops in which new cleaning practices might be developed to minimise any AMR bacteria present in the household environments located in the Greater Accra Region of Ghana. Microbiological analysis of household dust showed that 36.6% of bacterial isolates detected were found to carry at least one resistance to the panel of antibiotics tested. Four scenarios were generated from an economic segmentation of the survey data. 50 ethnographic insights were ‘presented’ and descriptions of 12 bacteria species that showed resistance to one or more antibiotics (representing 176 bacterial isolates that showed resistance to one or more antibiotics found in the dust samples) were presented to the participants in a codesign workshop. An intervention, a new regime of cleaning practices agreed through the co-design workshop and practiced for thirty days, was made in (n = 7) households. The high prevalence of multidrug resistance observed in this study indicate the need for antibiotics surveillance program, not only in hospital settings but also in the household environment. There is, thus, an urgent need for targeting of interventions at the household level. Activating knowledge through community engagement in the research helps in increasing public perception and breaking down the scientist-public barrier. |
format | Online Article Text |
id | pubmed-10307869 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-103078692023-06-30 Developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in Ghanaian homes Tsekleves, Emmanuel de Souza, Dziedzom Pickup, Roger Ahorlu, Collins Darby, Andy Sci Rep Article Globally Antimicrobial Resistance (AMR) constitutes a health crisis, particularly in developing countries, where infectious disease are commonly fatal. There is clear evidence for microbial exposure and infection transmission within the home. Personal and environmental hygiene are the best ways of reducing household infections thus decreasing the need for antibiotics and consequently diminishing AMR. Despite this being an obvious step, research efforts to understand the home environment and its impact on AMR, cleaning and possible interventions on household cleaning are limited. We combined design and microbiology methods in an innovative mixed-method approach. A traditional survey design (n = 240), a design ethnography (n = 12), a co-design workshop and a pre-intervention microbiological dust sample analysis was undertaken to provide insights for codesign workshops in which new cleaning practices might be developed to minimise any AMR bacteria present in the household environments located in the Greater Accra Region of Ghana. Microbiological analysis of household dust showed that 36.6% of bacterial isolates detected were found to carry at least one resistance to the panel of antibiotics tested. Four scenarios were generated from an economic segmentation of the survey data. 50 ethnographic insights were ‘presented’ and descriptions of 12 bacteria species that showed resistance to one or more antibiotics (representing 176 bacterial isolates that showed resistance to one or more antibiotics found in the dust samples) were presented to the participants in a codesign workshop. An intervention, a new regime of cleaning practices agreed through the co-design workshop and practiced for thirty days, was made in (n = 7) households. The high prevalence of multidrug resistance observed in this study indicate the need for antibiotics surveillance program, not only in hospital settings but also in the household environment. There is, thus, an urgent need for targeting of interventions at the household level. Activating knowledge through community engagement in the research helps in increasing public perception and breaking down the scientist-public barrier. Nature Publishing Group UK 2023-06-28 /pmc/articles/PMC10307869/ /pubmed/37380793 http://dx.doi.org/10.1038/s41598-023-37317-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Tsekleves, Emmanuel de Souza, Dziedzom Pickup, Roger Ahorlu, Collins Darby, Andy Developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in Ghanaian homes |
title | Developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in Ghanaian homes |
title_full | Developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in Ghanaian homes |
title_fullStr | Developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in Ghanaian homes |
title_full_unstemmed | Developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in Ghanaian homes |
title_short | Developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in Ghanaian homes |
title_sort | developing home cleaning intervention through community engagement to reduce infections and antimicrobial resistance in ghanaian homes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307869/ https://www.ncbi.nlm.nih.gov/pubmed/37380793 http://dx.doi.org/10.1038/s41598-023-37317-4 |
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