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Quality by design paradigm for optimization of green stability indicating HPLC method for concomitant determination of fluorescein and benoxinate
A green, robust and fast stability indicating chromatographic method has been developed for concomitant analysis of fluorescein sodium and benoxinate hydrochloride in the presence of their degradation products within four minutes. Two different designs including fractional factorial and Box–Behnken...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307890/ https://www.ncbi.nlm.nih.gov/pubmed/37380783 http://dx.doi.org/10.1038/s41598-023-37548-5 |