Imatinib associated temporal bone osteonecrosis

Tyrosine kinase inhibitors have substantially improved survival in patients with gastrointestinal stromal tumors (GIST) and chronic myeloid leukemia (CML). We report the first association between long‐term imatinib use and temporal bone osteonecrosis, highlighting the importance of prompt ENT evalua...

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Detalles Bibliográficos
Autores principales: McKenna, Dominic, Reddy, Ekambar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307993/
https://www.ncbi.nlm.nih.gov/pubmed/37397584
http://dx.doi.org/10.1002/ccr3.7611
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author McKenna, Dominic
Reddy, Ekambar
author_facet McKenna, Dominic
Reddy, Ekambar
author_sort McKenna, Dominic
collection PubMed
description Tyrosine kinase inhibitors have substantially improved survival in patients with gastrointestinal stromal tumors (GIST) and chronic myeloid leukemia (CML). We report the first association between long‐term imatinib use and temporal bone osteonecrosis, highlighting the importance of prompt ENT evaluation of such patients with new otological symptoms.
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spelling pubmed-103079932023-06-30 Imatinib associated temporal bone osteonecrosis McKenna, Dominic Reddy, Ekambar Clin Case Rep Case Images Tyrosine kinase inhibitors have substantially improved survival in patients with gastrointestinal stromal tumors (GIST) and chronic myeloid leukemia (CML). We report the first association between long‐term imatinib use and temporal bone osteonecrosis, highlighting the importance of prompt ENT evaluation of such patients with new otological symptoms. John Wiley and Sons Inc. 2023-06-28 /pmc/articles/PMC10307993/ /pubmed/37397584 http://dx.doi.org/10.1002/ccr3.7611 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Images
McKenna, Dominic
Reddy, Ekambar
Imatinib associated temporal bone osteonecrosis
title Imatinib associated temporal bone osteonecrosis
title_full Imatinib associated temporal bone osteonecrosis
title_fullStr Imatinib associated temporal bone osteonecrosis
title_full_unstemmed Imatinib associated temporal bone osteonecrosis
title_short Imatinib associated temporal bone osteonecrosis
title_sort imatinib associated temporal bone osteonecrosis
topic Case Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307993/
https://www.ncbi.nlm.nih.gov/pubmed/37397584
http://dx.doi.org/10.1002/ccr3.7611
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