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Evaluation of Senescence and Its Prevention in Doxorubicin-Induced Cardiotoxicity Using Dynamic Engineered Heart Tissues

BACKGROUND: Doxorubicin is an essential cancer treatment, but its usefulness is hampered by the occurrence of cardiotoxicity. Nevertheless, the pathophysiology underlying doxorubicin-induced cardiotoxicity and the respective molecular mechanisms are poorly understood. Recent studies have suggested i...

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Detalles Bibliográficos
Autores principales:	Linders, Annet N., Dias, Itamar B., Ovchinnikova, Ekaterina S., Vermeer, Mathilde C.S.C., Hoes, Martijn F., Markousis Mavrogenis, George, Deiman, Frederik E., Arevalo Gomez, Karla F., Bliley, Jacqueline M., Nehme, Jamil, Vink, Aryan, Gietema, Jourik, de Boer, Rudolf A., Westenbrink, Daan, Sillje, Herman H.W., Hilfiker-Kleiner, Denise, van Laake, Linda W., Feinberg, Adam W., Demaria, Marco, Bomer, Nils, van der Meer, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308053/ https://www.ncbi.nlm.nih.gov/pubmed/37397084 http://dx.doi.org/10.1016/j.jaccao.2023.03.012

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