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Emerging role of ubiquitination/deubiquitination modification of PD-1/PD-L1 in cancer immunotherapy
As members of the immune checkpoint family, PD-1 and its ligand PD-L1 play critical roles in maintaining the balance between autoimmunity and tolerance. The interaction of PD-1/PD-L1 is also involved in tumor evasion inside the tumor microenvironment, caused by reduced T cell activation, proliferati...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308071/ https://www.ncbi.nlm.nih.gov/pubmed/37396527 http://dx.doi.org/10.1016/j.gendis.2022.01.002 |