Emerging role of ubiquitination/deubiquitination modification of PD-1/PD-L1 in cancer immunotherapy

As members of the immune checkpoint family, PD-1 and its ligand PD-L1 play critical roles in maintaining the balance between autoimmunity and tolerance. The interaction of PD-1/PD-L1 is also involved in tumor evasion inside the tumor microenvironment, caused by reduced T cell activation, proliferati...

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Detalles Bibliográficos
Autores principales: Ding, Peng, Ma, Zhiqiang, Fan, Yizeng, Feng, Yingtong, Shao, Changjian, Pan, Minghong, Zhang, Yimeng, Huang, Di, Han, Jing, Hu, Yi, Yan, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308071/
https://www.ncbi.nlm.nih.gov/pubmed/37396527
http://dx.doi.org/10.1016/j.gendis.2022.01.002

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