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Modulation of SIRT6 activity acts as an emerging therapeutic implication for pathological disorders in the skeletal system

The skeletal system is a dynamically balanced system, which undergoes continuous bone resorption and formation to maintain bone matrix homeostasis. As an important ADP-ribosylase and NAD(+)-dependent deacylase, SIRT6 (SIR2-like protein 6) is widely expressed on various kinds of bone cells, such as c...

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Detalles Bibliográficos
Autores principales: Dong, Zicai, Yang, Chuan, Tan, Jiulin, Dou, Ce, Chen, Yueqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308074/
https://www.ncbi.nlm.nih.gov/pubmed/37396554
http://dx.doi.org/10.1016/j.gendis.2021.12.024