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Nuclear shapes are geometrically determined by the excess surface area of the nuclear lamina

Introduction: Nuclei have characteristic shapes dependent on cell type, which are critical for proper cell function, and nuclei lose their distinct shapes in multiple diseases including cancer, laminopathies, and progeria. Nuclear shapes result from deformations of the sub-nuclear components—nuclear...

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Detalles Bibliográficos
Autores principales: Dickinson, Richard B., Lele, Tanmay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308086/
https://www.ncbi.nlm.nih.gov/pubmed/37397244
http://dx.doi.org/10.3389/fcell.2023.1058727