A novel aptamer-based small RNA delivery platform and its application to cancer therapy

Major challenges such as nuclease degradation, rapid renal clearance, non-specific delivery, poor cellular uptake and inflammatory response have limited the clinical application of small RNA-mediated gene silencing. To overcome these challenges, we designed a novel targeting small RNA delivery platf...

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Detalles Bibliográficos
Autores principales: Tanno, Toshihiko, Zhang, Peng, Bailey, Christopher, Wang, Yin, Ittiprasert, Wannaporn, Devenport, Martin, Zheng, Pan, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308127/
https://www.ncbi.nlm.nih.gov/pubmed/37396505
http://dx.doi.org/10.1016/j.gendis.2022.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308127/
https://www.ncbi.nlm.nih.gov/pubmed/37396505
http://dx.doi.org/10.1016/j.gendis.2022.05.004

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