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Targeting SAMHD1: To overcome multiple anti-cancer drugs resistance in hematological malignancies
Sterile α motif and histidine/aspartic acid domain containing protein 1 (SAMHD1) is a deoxynucleoside triphosphate (dNTPs) triphosphohydrolase that can hydrolyze dNTPs into deoxynucleosides and triphosphates to keep the balance of the intracellular dNTPs pool. Moreover, it has been reported that SAM...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Chongqing Medical University
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308132/ https://www.ncbi.nlm.nih.gov/pubmed/37396510 http://dx.doi.org/10.1016/j.gendis.2022.06.001 |