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Ubx5‐Cdc48 assists the protease Wss1 at DNA‐protein crosslink sites in yeast

DNA‐protein crosslinks (DPCs) pose a serious threat to genome stability. The yeast proteases Wss1, 26S proteasome, and Ddi1 are safeguards of genome integrity by acting on a plethora of DNA‐bound proteins in different cellular contexts. The AAA ATPase Cdc48/p97 is known to assist Wss1/SPRTN in clear...

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Detalles Bibliográficos
Autores principales: Noireterre, Audrey, Serbyn, Nataliia, Bagdiul, Ivona, Stutz, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308373/
https://www.ncbi.nlm.nih.gov/pubmed/37144685
http://dx.doi.org/10.15252/embj.2023113609