The MyD88 inhibitor, ST2825, induces cell cycle arrest and apoptosis by suppressing the activation of the NF‑κB/AKT1/p21 pathway in pancreatic cancer

NF-κB activation occurs in the majority patients with pancreatic ductal adenocarcinoma (PDAC); however, directly targeting NF-κB has proven unsuccessful, and recent studies have demonstrated a certain effect of the indirect inhibition of NF-κB. Myeloid differentiation factor 88 (MyD88) is a common i...

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Detalles Bibliográficos
Autores principales: Lu, Sinan, He, Tianyu, Zhang, Yuan, Zhou, Bo, Zhang, Qiyi, Yan, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308493/
https://www.ncbi.nlm.nih.gov/pubmed/37326109
http://dx.doi.org/10.3892/or.2023.8585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308493/
https://www.ncbi.nlm.nih.gov/pubmed/37326109
http://dx.doi.org/10.3892/or.2023.8585

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