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Alzheimer’s disease biomarkers in cerebrospinal fluid are stable with the Elecsys immunoassay to most pre-analytical influencing factors except freezing at -80 °C

BACKGROUND: Alzheimer´s disease is considered a neurodegenerative disease and is diagnosed by exclusion, while the detection of specific cerebrospinal fluid (CSF) biomarkers, namely amyloid-beta (Aβ) peptides Aβ1–42 (Aß42), phospho-tau (181P; P-tau), and total-tau (T-tau), has been shown to improve...

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Detalles Bibliográficos
Autores principales: Konen, Franz Felix, Maier, Hannah Benedictine, Neyazi, Alexandra, Bleich, Stefan, Neumann, Konstantin, Skripuletz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308606/
https://www.ncbi.nlm.nih.gov/pubmed/37381021
http://dx.doi.org/10.1186/s42466-023-00257-5