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Metal-organic framework-encapsulated dihydroartemisinin nanoparticles induces apoptotic cell death in ovarian cancer by blocking ROMO1-mediated ROS production
Dihydroartemisinin (DHA), a natural product derived from the herbal medicine Artemisia annua, is recently used as a novel anti-cancer agent. However, some intrinsic disadvantages limit its potential for clinical management of cancer patients, such as poor water solubility and low bioavailability. No...
Autores principales: | Yan, Yuanliang, Yang, Xiaoxin, Han, Ning, Liu, Yuanhong, Liang, Qiuju, Li, Liu-Gen, Hu, Jun, Li, Tong-Fei, Xu, Zhijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308639/ https://www.ncbi.nlm.nih.gov/pubmed/37386404 http://dx.doi.org/10.1186/s12951-023-01959-3 |
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