Cargando…

Nesfatin-3 possesses divalent metal ion binding properties, which remain hidden in the nucleobindin-2 precursor protein

BACKGROUND: Nucleobindin-2 (Nucb2) is a multidomain protein that, due to its structure, participates in many physiological processes. It was originally identified in several regions of the hypothalamus. However, more recent studies have redefined and extended the function of Nucb2 far beyond its ini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Skorupska-Stasiak, Anna, Bystranowska, Dominika, Tran, Józef Ba, Krężel, Artur, Ożyhar, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308643/ https://www.ncbi.nlm.nih.gov/pubmed/37386441 http://dx.doi.org/10.1186/s12964-023-01181-6

Ejemplares similares

Nucleobindin-2 consists of two structural components: The Zn(2+)-sensitive N-terminal half, consisting of nesfatin-1 and -2, and the Ca(2+)-sensitive C-terminal half, consisting of nesfatin-3
por: Bystranowska, Dominika, et al.
Publicado: (2021)

The Multifaceted Nature of Nucleobindin-2 in Carcinogenesis
por: Skorupska, Anna, et al.
Publicado: (2021)

Does one plus one always equal two? Structural differences between nesfatin-1, -2, and nesfatin-1/2
por: Lenda, Rafał, et al.
Publicado: (2022)

Nucleobindin-2/Nesfatin-1—A New Cancer Related Molecule?
por: Kmiecik, Alicja M., et al.
Publicado: (2021)

Transgenic mice overexpressing nesfatin/nucleobindin-2 are susceptible to high-fat diet-induced obesity
por: Shimizu, H, et al.
Publicado: (2016)

Nucleobindin‐2/nesfatin‐1 enhances the cell proliferation, migration, invasion and epithelial‐mesenchymal transition in gastric carcinoma
por: Ren, Le, et al.
Publicado: (2022)

Nesfatin-1/Nucleobindin-2 Is a Potent Prognostic Marker and Enhances Cell Proliferation, Migration, and Invasion in Bladder Cancer
por: Liu, Guang-Ming, et al.
Publicado: (2018)

Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish
por: Montesano, Alessia, et al.
Publicado: (2019)

Nesfatin-1-Like Peptide Encoded in Nucleobindin-1 in Goldfish is a Novel Anorexigen Modulated by Sex Steroids, Macronutrients and Daily Rhythm
por: Sundarrajan, Lakshminarasimhan, et al.
Publicado: (2016)

SAT-LB102 Obesity Is Associated With Reduced Expression of the Anorexigenic Neuropeptide Nucleobindin-2/Nesfatin-1 in the Human Nucleus of the Solitary Tract
por: Psilopanagioti, Aristea, et al.
Publicado: (2020)

Nutrients Differentially Regulate Nucleobindin-2/Nesfatin-1 In Vitro in Cultured Stomach Ghrelinoma (MGN3-1) Cells and In Vivo in Male Mice
por: Mohan, Haneesha, et al.
Publicado: (2014)

Glucagon-like Peptide-1 Receptor in the Human Hypothalamus Is Associated with Body Mass Index and Colocalizes with the Anorexigenic Neuropeptide Nucleobindin-2/Nesfatin-1
por: Psilopanagioti, Aristea, et al.
Publicado: (2022)

Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer
por: Kan, Jung-Yu, et al.
Publicado: (2016)

Deep blue autofluorescence reflects the oxidation state of human transthyretin
por: Wieczorek, Elżbieta, et al.
Publicado: (2022)

InterMetalDB: A Database and Browser of Intermolecular Metal Binding Sites in Macromolecules with Structural Information
por: Tran, Józef Ba, et al.
Publicado: (2021)

Nucleobindin 2 expression is an independent prognostic factor for bladder cancer
por: Cho, Jeong Man, et al.
Publicado: (2020)

Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma
por: Lin, I-Cheng, et al.
Publicado: (2023)

The intrinsically disordered region of GCE protein adopts a more fixed structure by interacting with the LBD of the nuclear receptor FTZ-F1
por: Kolonko, Marta, et al.
Publicado: (2020)

Relations between Structure and Zn(II) Binding Affinity Shed Light on the Mechanisms of Rad50 Hook Domain Functioning and Its Phosphorylation
por: Tran, Józef Ba, et al.
Publicado: (2022)

Nucleobindin Co-Localizes and Associates with Cyclooxygenase (COX)-2 in Human Neutrophils
por: Leclerc, Patrick, et al.
Publicado: (2008)

Nucleobindin-2 enhances the epithelial-mesenchymal transition in renal cell carcinoma
por: Tao, Ran, et al.
Publicado: (2020)

High Expression of Nucleobindin-2 Is Associated With Poor Prognosis in Gastric Cancer
por: Okada, Junichi, et al.
Publicado: (2021)

The RNA-Binding and RNA-Melting Activities of the Multifunctional Protein Nucleobindin 1
por: Mikhaylina, Alisa, et al.
Publicado: (2023)

The Mammalian Calcium-binding Protein, Nucleobindin (CALNUC), Is a Golgi Resident Protein
por: Lin, Ping, et al.
Publicado: (1998)

Secreted Nucleobindin-2 Inhibits 3T3-L1 Adipocyte Differentiation
por: Tagaya, Yuko, et al.
Publicado: (2012)

Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization
por: Bonito-Oliva, Alessandra, et al.
Publicado: (2017)

Nucleobindin-1 regulates ECM degradation by promoting intra-Golgi trafficking of MMPs
por: Pacheco-Fernandez, Natalia, et al.
Publicado: (2020)

Possible Association of Nucleobindin-1 Protein with Depressive Disorder in Patients with HIV Infection
por: Yang, Yun, et al.
Publicado: (2022)

Hidden lesions: a case of burnt remains
por: Moghaddam, Negahnaz, et al.
Publicado: (2023)

Overexpression of CALNUC (Nucleobindin) Increases Agonist and Thapsigargin Releasable Ca(2+) Storage in the Golgi
por: Lin, Ping, et al.
Publicado: (1999)

Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity
por: Ravussin, Anthony, et al.
Publicado: (2018)

MON-313 High Expression of Nucleobindin-2 Is Associated with Poor Prognosis in Gastric Cancer
por: Okada, Shuichi, et al.
Publicado: (2019)

Function theory on manifolds which possess a pole
por: Greene, R E, et al.
Publicado: (1979)

Leprosy: making good progress but hidden challenges remain
por: Smith, W. Cairns S.
Publicado: (2013)

Nucleoplasmin-like domain of FKBP39 from Drosophila melanogaster forms a tetramer with partly disordered tentacle-like C-terminal segments
por: Kozłowska, Małgorzata, et al.
Publicado: (2017)

Current Understanding of the Role of Nesfatin-1
por: Schalla, Martha A, et al.
Publicado: (2018)

Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?
por: Wood, Valerie, et al.
Publicado: (2019)

Divalent cation tolerance protein binds to β-secretase and inhibits the processing of amyloid precursor protein☆
por: Liu, Runzhong, et al.
Publicado: (2013)

HCV cure for everyone or which challenges remain?
por: Rockstroh, Jürgen Kurt
Publicado: (2015)

Tissue-Specific Modulation of Gluco- and Growth-Regulatory Factor Abundance by Nesfatin-1 and Nesfatin-1-like Peptide in Goldfish
por: Rajeswari, Jithine Jayakumar, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5b3ilicjp1b3nr2rtvc7qiel9k