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Increase in power by obtaining 10 or more controls per case when type-1 error is small in large-scale association studies
BACKGROUND: The rule of thumb that there is little gain in statistical power by obtaining more than 4 controls per case, is based on type-1 error α = 0.05. However, association studies that evaluate thousands or millions of associations use smaller α and may have access to plentiful controls. We inv...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308790/ https://www.ncbi.nlm.nih.gov/pubmed/37386403 http://dx.doi.org/10.1186/s12874-023-01973-x |