The Highly Conserved Stem-Loop II Motif Is Dispensable for SARS-CoV-2

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The stem-loop II motif (s2m) is an RNA structural element that is found in the 3′ untranslated region (UTR) of many RNA viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Though the motif was discovered over 25 years ago, its functional significance is unknown. In order...

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Detalles Bibliográficos
Autores principales: Jiang, Hongbing, Joshi, Astha, Gan, Tianyu, Janowski, Andrew B., Fujii, Chika, Bricker, Traci L., Darling, Tamarand L., Harastani, Houda H., Seehra, Kuljeet, Chen, Hongwei, Tahan, Stephen, Jung, Ana, Febles, Binita, Blatter, Joshua A., Handley, Scott A., Parikh, Bijal A., Wang, David, Boon, Adrianus C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308922/
https://www.ncbi.nlm.nih.gov/pubmed/37223945
http://dx.doi.org/10.1128/jvi.00635-23

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