Lp-PLA2 silencing ameliorates inflammation and autophagy in nonalcoholic steatohepatitis through inhibiting the JAK2/STAT3 pathway

BACKGROUND: Nonalcoholic steatohepatitis (NASH), a common cause of liver-related morbidity and mortality worldwide, is characterized by inflammation and hepatocellular injury. Our research focuses on lipoprotein-associated phospholipase A2 (Lp-PLA2), an inflammation-related biomarker that has recent...

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Detalles Bibliográficos
Autores principales: Yao, Jinmei, Zhao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309053/
https://www.ncbi.nlm.nih.gov/pubmed/37397012
http://dx.doi.org/10.7717/peerj.15639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309053/
https://www.ncbi.nlm.nih.gov/pubmed/37397012
http://dx.doi.org/10.7717/peerj.15639

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