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Pharmacogenetic interactions of efavirenz or rifampin and isoniazid with levonorgestrel emergency contraception during treatment of HIV or tuberculosis

In AIDS Clinical Trials Group study A5375, a pharmacokinetic trial of levonorgestrel emergency contraception, double-dose levonorgestrel (3 mg, versus standard dose 1.5 mg) offset the induction effects of efavirenz or rifampin on plasma levonorgestrel exposure over 8 h post-dose (AUC(0-8h)). We char...

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Detalles Bibliográficos
Autores principales: Agyemang, Nana, Scarsi, Kimberly K., Baker, Paxton, Smeaton, Laura M., Podany, Anthony T., Olefsky, Maxine, Woolley, Elizabeth, Barr, Elizabeth, Pham, Michelle, Mawlana, Sajeeda, Supparatpinyo, Khuanchai, Gatechompol, Sivaporn, Jalil, Emilia M., Gadama, Luis, Badal-Faesen, Sharlaa, Van Schalkwyk, Marije, Kayama, Cecelia, Belaunzaran-Zamudio, Pablo F., Godfrey, Catherine, Cohn, Susan E., Mngqibisa, Rosie, Haas, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309098/
https://www.ncbi.nlm.nih.gov/pubmed/37306344
http://dx.doi.org/10.1097/FPC.0000000000000501