A PI(3,5)P(2) reporter reveals PIKfyve activity and dynamics on macropinosomes and phagosomes

Phosphoinositide signaling lipids (PIPs) are key regulators of membrane identity and trafficking. Of these, PI(3,5)P(2) is one of the least well-understood, despite key roles in many endocytic pathways including phagocytosis and macropinocytosis. PI(3,5)P(2) is generated by the phosphoinositide 5-ki...

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Detalles Bibliográficos
Autores principales: Vines, James H., Maib, Hannes, Buckley, Catherine M., Gueho, Aurelie, Zhu, Zhou, Soldati, Thierry, Murray, David H., King, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Tools
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309190/
https://www.ncbi.nlm.nih.gov/pubmed/37382666
http://dx.doi.org/10.1083/jcb.202209077

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