Cargando…

Update on Thrombocytopenia in Pregnancy

Thrombocytopenia, defined as platelet count < 150,000 mm (3) , is frequently diagnosed by obstetricians since this parameter is included in routine surveillance during pregnancy, with an incidence of between 7 and 12%. Therefore, decisions regarding subsequent examination and management are primo...

Descripción completa

Detalles Bibliográficos
Autores principales: Subtil, Simone Filipa Carrasqueira, Mendes, Jorge Miguel Bastos, Areia, Ana Luísa Fialho de Amaral, Moura, José Paulo Achando Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda. 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309201/
https://www.ncbi.nlm.nih.gov/pubmed/33348401
http://dx.doi.org/10.1055/s-0040-1721350
Descripción
Sumario:Thrombocytopenia, defined as platelet count < 150,000 mm (3) , is frequently diagnosed by obstetricians since this parameter is included in routine surveillance during pregnancy, with an incidence of between 7 and 12%. Therefore, decisions regarding subsequent examination and management are primordial. While most of the cases are due to physiological changes, as gestational thrombocytopenia, other causes can be related to severe conditions that can lead to fetal or maternal death. Differentiating these conditions might be challenging: they can be pregnancy-specific (pre-eclampsia/HELLP syndrome [hemolysis, elevated liver enzymes, low platelets]), or not (immune thrombocytopenia purpura, thrombotic thrombocytopenic purpura or hemolytic uremic syndrome). Understanding the mechanisms and recognition of symptoms and signs is essential to decide an adequate line of investigation. The severity of thrombocytopenia, its etiology and gestational age dictates different treatment regimens.