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Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry
Objective To assess maternal and perinatal outcomes in pregnancies after kidney transplantation in a tertiary center in Brazil. Methods Retrospective cohort of pregnancies in women with kidney transplantation at the Universidade Estadual de Campinas, from January 1995 until December 2017. Medical ch...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Revinter Publicações Ltda
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309293/ https://www.ncbi.nlm.nih.gov/pubmed/31250419 http://dx.doi.org/10.1055/s-0039-1688834 |
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author | Mariano, Stephanye Guida, Jose Paulo de Siqueira Sousa, Marcos Vinicius de Parpinelli, Mary Angela Surita, Fernanda Garanhani Mazzali, Marilda Costa, Maria Laura |
author_facet | Mariano, Stephanye Guida, Jose Paulo de Siqueira Sousa, Marcos Vinicius de Parpinelli, Mary Angela Surita, Fernanda Garanhani Mazzali, Marilda Costa, Maria Laura |
author_sort | Mariano, Stephanye |
collection | PubMed |
description | Objective To assess maternal and perinatal outcomes in pregnancies after kidney transplantation in a tertiary center in Brazil. Methods Retrospective cohort of pregnancies in women with kidney transplantation at the Universidade Estadual de Campinas, from January 1995 until December 2017. Medical charts were reviewed, and maternal and perinatal outcomes were described as means and frequencies. Renal function and blood pressure were evaluated during pregnancy and postpartum. Results A total of 22 women had at least 1 pregnancy during the considered time interval, and 3 of them had > 1 pregnancy, totalizing 25 pregnancies. The mean age at transplantation was of 24.6 ± 4.2 years old, and the mean time interval until pregnancy was of 67.8 ± 46.3 months. The most frequent complication during pregnancy was hypertension, which affected 11 (64.7%) women. The gestational age at delivery was 34.7 ± 4 weeks, and 47% of these pregnancies were preterm (< 37 weeks). A total of 88.2% of the women delivered by cesarean section. Renal function, measured by serum creatinine, remained stable during pregnancy, and the systolic blood pressure increased significantly, while the diastolic blood pressure did not differ during pregnancy. Conclusion Pregnancy after kidney transplantation is a rare event. Pre-eclampsia and prematurity were frequent complications, and cesarean section rates were very high. A specialized antenatal and postpartum care with a multiprofessional approach and continuous monitoring of graft function are essential for the early diagnosis of complications and improved outcomes. |
format | Online Article Text |
id | pubmed-10309293 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Thieme Revinter Publicações Ltda |
record_format | MEDLINE/PubMed |
spelling | pubmed-103092932023-07-27 Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry Mariano, Stephanye Guida, Jose Paulo de Siqueira Sousa, Marcos Vinicius de Parpinelli, Mary Angela Surita, Fernanda Garanhani Mazzali, Marilda Costa, Maria Laura Rev Bras Ginecol Obstet Objective To assess maternal and perinatal outcomes in pregnancies after kidney transplantation in a tertiary center in Brazil. Methods Retrospective cohort of pregnancies in women with kidney transplantation at the Universidade Estadual de Campinas, from January 1995 until December 2017. Medical charts were reviewed, and maternal and perinatal outcomes were described as means and frequencies. Renal function and blood pressure were evaluated during pregnancy and postpartum. Results A total of 22 women had at least 1 pregnancy during the considered time interval, and 3 of them had > 1 pregnancy, totalizing 25 pregnancies. The mean age at transplantation was of 24.6 ± 4.2 years old, and the mean time interval until pregnancy was of 67.8 ± 46.3 months. The most frequent complication during pregnancy was hypertension, which affected 11 (64.7%) women. The gestational age at delivery was 34.7 ± 4 weeks, and 47% of these pregnancies were preterm (< 37 weeks). A total of 88.2% of the women delivered by cesarean section. Renal function, measured by serum creatinine, remained stable during pregnancy, and the systolic blood pressure increased significantly, while the diastolic blood pressure did not differ during pregnancy. Conclusion Pregnancy after kidney transplantation is a rare event. Pre-eclampsia and prematurity were frequent complications, and cesarean section rates were very high. A specialized antenatal and postpartum care with a multiprofessional approach and continuous monitoring of graft function are essential for the early diagnosis of complications and improved outcomes. Thieme Revinter Publicações Ltda 2019-06-16 2019-07 /pmc/articles/PMC10309293/ /pubmed/31250419 http://dx.doi.org/10.1055/s-0039-1688834 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Mariano, Stephanye Guida, Jose Paulo de Siqueira Sousa, Marcos Vinicius de Parpinelli, Mary Angela Surita, Fernanda Garanhani Mazzali, Marilda Costa, Maria Laura Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry |
title | Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry |
title_full | Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry |
title_fullStr | Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry |
title_full_unstemmed | Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry |
title_short | Pregnancy Among Women with Kidney Transplantation: A 20-Years Single-Center Registry |
title_sort | pregnancy among women with kidney transplantation: a 20-years single-center registry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309293/ https://www.ncbi.nlm.nih.gov/pubmed/31250419 http://dx.doi.org/10.1055/s-0039-1688834 |
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