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Early Age at First Sexual Intercourse is Associated with Higher Prevalence of High-grade Squamous Intraepithelial Lesions (HSIL)

Objective To evaluate the association of age at first sexual intercourse with the results of the cervicovaginal cytology. Study Design Observational analytical study about the prevalence of altered cervicovaginal cytology results in women aged between 18 and 34 years from a densely populated area in...

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Autores principales: Xavier-Júnior, José Cândido Caldeira, Dufloth, Rozany Mucha, Vale, Diama Bhadra, Lima, Marcelo Tavares de, Zeferino, Luiz Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme-Revinter Publicações Ltda 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309306/
https://www.ncbi.nlm.nih.gov/pubmed/28231601
http://dx.doi.org/10.1055/s-0036-1597973
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author Xavier-Júnior, José Cândido Caldeira
Dufloth, Rozany Mucha
Vale, Diama Bhadra
Lima, Marcelo Tavares de
Zeferino, Luiz Carlos
author_facet Xavier-Júnior, José Cândido Caldeira
Dufloth, Rozany Mucha
Vale, Diama Bhadra
Lima, Marcelo Tavares de
Zeferino, Luiz Carlos
author_sort Xavier-Júnior, José Cândido Caldeira
collection PubMed
description Objective To evaluate the association of age at first sexual intercourse with the results of the cervicovaginal cytology. Study Design Observational analytical study about the prevalence of altered cervicovaginal cytology results in women aged between 18 and 34 years from a densely populated area in Brazil, during 10 years. The patients were stratified into 2 categories according to their age at first sexual intercourse (13–16 years and 17–24 years). Results From the total of 2,505,154 exams, 898,921 tests were in accordance with the inclusion criteria. Considering women with 4 years or less from the first sexual intercourse as a reference, those with 5 to 9 years and 10 years or more showed a higher prevalence of high-grade squamous intraepithelial lesions (HSILs). Women with an earlier onset of sexual intercourse (13–16 years) showed higher prevalence ratios for atypical squamous cells (ASC), low-grade squamous intraepithelial lesion (LSIL) and HSIL. The prevalence ratio for HSIL adjusted by age at diagnosis and by age at first sexual intercourse was higher only for women with an earlier onset of sexual intercourse. Conclusions The age of first sexual intercourse could be a variable that might qualify the selection among young women who are really at a higher risk for HSIL.
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spelling pubmed-103093062023-07-27 Early Age at First Sexual Intercourse is Associated with Higher Prevalence of High-grade Squamous Intraepithelial Lesions (HSIL) Xavier-Júnior, José Cândido Caldeira Dufloth, Rozany Mucha Vale, Diama Bhadra Lima, Marcelo Tavares de Zeferino, Luiz Carlos Rev Bras Ginecol Obstet Objective To evaluate the association of age at first sexual intercourse with the results of the cervicovaginal cytology. Study Design Observational analytical study about the prevalence of altered cervicovaginal cytology results in women aged between 18 and 34 years from a densely populated area in Brazil, during 10 years. The patients were stratified into 2 categories according to their age at first sexual intercourse (13–16 years and 17–24 years). Results From the total of 2,505,154 exams, 898,921 tests were in accordance with the inclusion criteria. Considering women with 4 years or less from the first sexual intercourse as a reference, those with 5 to 9 years and 10 years or more showed a higher prevalence of high-grade squamous intraepithelial lesions (HSILs). Women with an earlier onset of sexual intercourse (13–16 years) showed higher prevalence ratios for atypical squamous cells (ASC), low-grade squamous intraepithelial lesion (LSIL) and HSIL. The prevalence ratio for HSIL adjusted by age at diagnosis and by age at first sexual intercourse was higher only for women with an earlier onset of sexual intercourse. Conclusions The age of first sexual intercourse could be a variable that might qualify the selection among young women who are really at a higher risk for HSIL. Thieme-Revinter Publicações Ltda 2017-02-23 2017-02 /pmc/articles/PMC10309306/ /pubmed/28231601 http://dx.doi.org/10.1055/s-0036-1597973 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Xavier-Júnior, José Cândido Caldeira
Dufloth, Rozany Mucha
Vale, Diama Bhadra
Lima, Marcelo Tavares de
Zeferino, Luiz Carlos
Early Age at First Sexual Intercourse is Associated with Higher Prevalence of High-grade Squamous Intraepithelial Lesions (HSIL)
title Early Age at First Sexual Intercourse is Associated with Higher Prevalence of High-grade Squamous Intraepithelial Lesions (HSIL)
title_full Early Age at First Sexual Intercourse is Associated with Higher Prevalence of High-grade Squamous Intraepithelial Lesions (HSIL)
title_fullStr Early Age at First Sexual Intercourse is Associated with Higher Prevalence of High-grade Squamous Intraepithelial Lesions (HSIL)
title_full_unstemmed Early Age at First Sexual Intercourse is Associated with Higher Prevalence of High-grade Squamous Intraepithelial Lesions (HSIL)
title_short Early Age at First Sexual Intercourse is Associated with Higher Prevalence of High-grade Squamous Intraepithelial Lesions (HSIL)
title_sort early age at first sexual intercourse is associated with higher prevalence of high-grade squamous intraepithelial lesions (hsil)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309306/
https://www.ncbi.nlm.nih.gov/pubmed/28231601
http://dx.doi.org/10.1055/s-0036-1597973
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