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Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy
In this case report, we discuss a case of pancreatic cancer bearing a BRAF fusion, leading to MAPK activation, MLHph, and finally MSI.
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309529/ https://www.ncbi.nlm.nih.gov/pubmed/37364232 http://dx.doi.org/10.1200/PO.22.00650 |
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author | Heinrich, Kathrin Fischer, Laura E. De Toni, Enrico N. Markwardt, Daniel Roessler, Daniel Beyer, Georg Günther, Michael Ormanns, Steffen Klauschen, Frederick Kunz, Wolfgang G. Fröhling, Stefan Brummer, Tilman Heinemann, Volker Westphalen, C. Benedikt |
author_facet | Heinrich, Kathrin Fischer, Laura E. De Toni, Enrico N. Markwardt, Daniel Roessler, Daniel Beyer, Georg Günther, Michael Ormanns, Steffen Klauschen, Frederick Kunz, Wolfgang G. Fröhling, Stefan Brummer, Tilman Heinemann, Volker Westphalen, C. Benedikt |
author_sort | Heinrich, Kathrin |
collection | PubMed |
description | In this case report, we discuss a case of pancreatic cancer bearing a BRAF fusion, leading to MAPK activation, MLHph, and finally MSI. |
format | Online Article Text |
id | pubmed-10309529 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-103095292023-06-30 Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy Heinrich, Kathrin Fischer, Laura E. De Toni, Enrico N. Markwardt, Daniel Roessler, Daniel Beyer, Georg Günther, Michael Ormanns, Steffen Klauschen, Frederick Kunz, Wolfgang G. Fröhling, Stefan Brummer, Tilman Heinemann, Volker Westphalen, C. Benedikt JCO Precis Oncol Case Reports In this case report, we discuss a case of pancreatic cancer bearing a BRAF fusion, leading to MAPK activation, MLHph, and finally MSI. Wolters Kluwer Health 2023-06-26 /pmc/articles/PMC10309529/ /pubmed/37364232 http://dx.doi.org/10.1200/PO.22.00650 Text en © 2023 by American Society of Clinical Oncology https://creativecommons.org/licenses/by-nc-nd/4.0/Creative Commons Attribution Non-Commercial No Derivatives 4.0 License: http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Case Reports Heinrich, Kathrin Fischer, Laura E. De Toni, Enrico N. Markwardt, Daniel Roessler, Daniel Beyer, Georg Günther, Michael Ormanns, Steffen Klauschen, Frederick Kunz, Wolfgang G. Fröhling, Stefan Brummer, Tilman Heinemann, Volker Westphalen, C. Benedikt Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy |
title | Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy |
title_full | Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy |
title_fullStr | Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy |
title_full_unstemmed | Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy |
title_short | Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy |
title_sort | case of a patient with pancreatic cancer with sporadic microsatellite instability associated with a braf fusion achieving excellent response to immunotherapy |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309529/ https://www.ncbi.nlm.nih.gov/pubmed/37364232 http://dx.doi.org/10.1200/PO.22.00650 |
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