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Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy

In this case report, we discuss a case of pancreatic cancer bearing a BRAF fusion, leading to MAPK activation, MLHph, and finally MSI.

Detalles Bibliográficos
Autores principales: Heinrich, Kathrin, Fischer, Laura E., De Toni, Enrico N., Markwardt, Daniel, Roessler, Daniel, Beyer, Georg, Günther, Michael, Ormanns, Steffen, Klauschen, Frederick, Kunz, Wolfgang G., Fröhling, Stefan, Brummer, Tilman, Heinemann, Volker, Westphalen, C. Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309529/
https://www.ncbi.nlm.nih.gov/pubmed/37364232
http://dx.doi.org/10.1200/PO.22.00650
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author Heinrich, Kathrin
Fischer, Laura E.
De Toni, Enrico N.
Markwardt, Daniel
Roessler, Daniel
Beyer, Georg
Günther, Michael
Ormanns, Steffen
Klauschen, Frederick
Kunz, Wolfgang G.
Fröhling, Stefan
Brummer, Tilman
Heinemann, Volker
Westphalen, C. Benedikt
author_facet Heinrich, Kathrin
Fischer, Laura E.
De Toni, Enrico N.
Markwardt, Daniel
Roessler, Daniel
Beyer, Georg
Günther, Michael
Ormanns, Steffen
Klauschen, Frederick
Kunz, Wolfgang G.
Fröhling, Stefan
Brummer, Tilman
Heinemann, Volker
Westphalen, C. Benedikt
author_sort Heinrich, Kathrin
collection PubMed
description In this case report, we discuss a case of pancreatic cancer bearing a BRAF fusion, leading to MAPK activation, MLHph, and finally MSI.
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spelling pubmed-103095292023-06-30 Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy Heinrich, Kathrin Fischer, Laura E. De Toni, Enrico N. Markwardt, Daniel Roessler, Daniel Beyer, Georg Günther, Michael Ormanns, Steffen Klauschen, Frederick Kunz, Wolfgang G. Fröhling, Stefan Brummer, Tilman Heinemann, Volker Westphalen, C. Benedikt JCO Precis Oncol Case Reports In this case report, we discuss a case of pancreatic cancer bearing a BRAF fusion, leading to MAPK activation, MLHph, and finally MSI. Wolters Kluwer Health 2023-06-26 /pmc/articles/PMC10309529/ /pubmed/37364232 http://dx.doi.org/10.1200/PO.22.00650 Text en © 2023 by American Society of Clinical Oncology https://creativecommons.org/licenses/by-nc-nd/4.0/Creative Commons Attribution Non-Commercial No Derivatives 4.0 License: http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Case Reports
Heinrich, Kathrin
Fischer, Laura E.
De Toni, Enrico N.
Markwardt, Daniel
Roessler, Daniel
Beyer, Georg
Günther, Michael
Ormanns, Steffen
Klauschen, Frederick
Kunz, Wolfgang G.
Fröhling, Stefan
Brummer, Tilman
Heinemann, Volker
Westphalen, C. Benedikt
Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy
title Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy
title_full Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy
title_fullStr Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy
title_full_unstemmed Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy
title_short Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a BRAF Fusion Achieving Excellent Response to Immunotherapy
title_sort case of a patient with pancreatic cancer with sporadic microsatellite instability associated with a braf fusion achieving excellent response to immunotherapy
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309529/
https://www.ncbi.nlm.nih.gov/pubmed/37364232
http://dx.doi.org/10.1200/PO.22.00650
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