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HTLV-1 Hbz protein, but not hbz mRNA secondary structure, is critical for viral persistence and disease development
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic cause of adult T-cell leukemia/lymphoma (ATL) and encodes a viral oncoprotein (Hbz) that is consistently expressed in asymptomatic carriers and ATL patients, suggesting its importance in the development and maintenance of HTLV-1 leukemic c...
Autores principales: | Maksimova, Victoria, Wilkie, Tasha, Smith, Susan, Phelps, Cameron, Melvin, Corrine, Yu, Lianbo, Niewiesk, Stefan, Green, Patrick L., Panfil, Amanda R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10309998/ https://www.ncbi.nlm.nih.gov/pubmed/37327244 http://dx.doi.org/10.1371/journal.ppat.1011459 |
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