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Whole-cell modeling of E. coli colonies enables quantification of single-cell heterogeneity in antibiotic responses
Antibiotic resistance poses mounting risks to human health, as current antibiotics are losing efficacy against increasingly resistant pathogenic bacteria. Of particular concern is the emergence of multidrug-resistant strains, which has been rapid among Gram-negative bacteria such as Escherichia coli...
Autores principales: | Skalnik, Christopher J., Cheah, Sean Y., Yang, Mica Y., Wolff, Mattheus B., Spangler, Ryan K., Talman, Lee, Morrison, Jerry H., Peirce, Shayn M., Agmon, Eran, Covert, Markus W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310025/ https://www.ncbi.nlm.nih.gov/pubmed/37327241 http://dx.doi.org/10.1371/journal.pcbi.1011232 |
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